NCT06977919

Brief Summary

This RCT investigates a 12-week NASM OPT program targeting pectoral muscle strength, breast aesthetics (firmness, lift, chest circumference), and low back pain in 120 non-athletic women. The intervention group performed structured resistance training, while the control group engaged in general exercise. Outcomes included pectoral strength (dynamometer), aesthetic satisfaction (Likert scale), and functional performance (push-up test).

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P75+ for not_applicable low-back-pain

Timeline
Completed

Started May 2025

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2025

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

May 10, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 18, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2025

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2026

Completed
Last Updated

May 6, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

May 10, 2025

Last Update Submit

April 29, 2026

Conditions

Low Back PainMuscle WeaknessBreast Sagging

Keywords

NASM OPTPectoral MusclesBreast FirmnessNon-Athletic WomenResistance Training

Outcome Measures

Primary Outcomes (6)

  • Pectoral Strength

    Kilogram (kg); handheld dynamometer

    Baseline

  • Perceived Breast Firmness/Lift

    5-point Likert scale

    Baseline

  • Chest Circumference

    Centimeter (cm)

    Baseline

  • Aesthetic Satisfaction

    5-point Likert scale

    Baseline

  • Functional Performance

    30-second push-up test

    Baseline

  • Low Back Pain

    VAS, 0-10 cm

    Baseline

Secondary Outcomes (6)

  • Aesthetic Satisfaction

    After12 weeks (post-intervention)

  • Functional Performance

    After12 weeks (post-intervention)

  • Low Back Pain

    After12 weeks (post-intervention)

  • Pectoral Strength

    After12 weeks (post-intervention)

  • Perceived Breast Firmness/Lift

    After12 weeks (post-intervention)

  • +1 more secondary outcomes

Study Arms (2)

NASM OPT Group

EXPERIMENTAL

Three 60-minute weekly sessions for 12 weeks, progressing through stabilization (weeks 1-4), strength endurance (weeks 5-8), and hypertrophy (weeks 9-12) phases. Exercises included bench presses, chest flyes, and push-ups.

Behavioral: NASM OPT Program

General Exercise Group

ACTIVE COMPARATOR

Three 60-minute weekly sessions of brisk walking and light aerobics without targeted resistance training.

Behavioral: General Exercise

Interventions

NASM OPT ProgramBEHAVIORAL

Three 60-minute weekly sessions for 12 weeks, progressing through stabilization (weeks 1-4), strength endurance (weeks 5-8), and hypertrophy (weeks 9-12) phases. Exercises included bench presses, chest flyes, and push-ups.

Also known as: Experimental
NASM OPT Group
General ExerciseBEHAVIORAL

Three 60-minute weekly sessions of brisk walking and light aerobics without targeted resistance training.

Also known as: Active Comparator
General Exercise Group

Eligibility Criteria

Age20 Years - 45 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Non-athletic women (no exercise in prior 6 months).
  • Interest in improving chest aesthetics.
  • No musculoskeletal injuries.

You may not qualify if:

  • Pregnancy
  • Chronic illness
  • Exercise contraindications

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sport Sciences Department

Zahedan, Sistan and Baluchestan, 9816744818, Iran

Location

MeSH Terms

Conditions

Low Back PainMuscle Weakness

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMuscular DiseasesMusculoskeletal DiseasesNeuromuscular ManifestationsNervous System DiseasesPathologic Processes

Study Officials

  • Mohammadreza Rezaeipour, MD, PhD

    Assoc.Prof.Dr.

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Single-blind (outcome assessors only; participants/instructors unblinded due to intervention nature).
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assoc.Prof.Dr.

Study Record Dates

First Submitted

May 10, 2025

First Posted

May 18, 2025

Study Start

May 1, 2025

Primary Completion

September 15, 2025

Study Completion

April 30, 2026

Last Updated

May 6, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Privacy concerns regarding sensitive participant data.

Locations

IR(1)