Upper Eyelid Dynamics in Pediatric Blepharoptosis Using High Speed Videography

NCT06976645 | Not Yet Recruiting

• 1 other identifier: UEL dynamics in cong.ptosis
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Evaluation of the Upper Eyelid Dynamics in Simple Congenital Blepharoptosis before and after Levator Muscle Resection Using High speed Photography

Conditions

Upper Eyelid Dynamics

Outcome Measures

Primary Outcomes (1)

• Determine the changes of blinking velocity before and after levator resection in patients with congenital ptosis

  Record the changes of blinking velocity in patients with congenital ptosis before and after levator resection \&normal patients in same age group using high speed videography to detect changes in blinking velocity .

  One year

Study Arms (1)

Levatot muscle resection

OTHER

Levator muscle resection for correction of upper eyelid congenital blepharoptosis

Procedure: Levator muscle resection

Interventions

Levator muscle resection PROCEDURE

Levator muscle resection

Levatot muscle resection

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients who are diagnosed as simple congenital ptosis with fair to good levator function (≥5 mm lid elevation) with age range from 5 to 18 years old.

You may not qualify if:

• Patients with a history of previous eyelid surgery or trauma
• Blepharophamosis and Marcus Gun Jaw-winking syndrome
• Patients with associated neurological disorders
• Patients with craniofacial abnormalities
• Patients with suspected myasthenia or myopathies
• Patients with absent Bell's phenomenon
• Patients with dry eye
• Uncooperative patients

Sponsors & Collaborators

• Minia University: lead

Related Publications (5)

• Hung G, Hsu F, Stark L. Dynamics of the human eyeblink. Am J Optom Physiol Opt. 1977 Oct;54(10):678-90. doi: 10.1097/00006324-197710000-00005.

  PMID: 605924 BACKGROUND

• DeAngelis KD, Rider A, Potter W, Jensen J, Fowler BT, Fleming JC. Eyelid Spontaneous Blink Analysis and Age-Related Changes Through High-Speed Imaging. Ophthalmic Plast Reconstr Surg. 2019 Sep/Oct;35(5):487-490. doi: 10.1097/IOP.0000000000001349.

  PMID: 30844914 BACKGROUND

• Mak FHW, Ting M, Edmunds MR, Harker A, Edirisinghe M, Duggineni S, Murta F, Ezra DG. Videographic Analysis of Blink Dynamics following Upper Eyelid Blepharoplasty and Its Association with Dry Eye. Plast Reconstr Surg Glob Open. 2020 Jul 21;8(7):e2991. doi: 10.1097/GOX.0000000000002991. eCollection 2020 Jul.

  PMID: 32802679 BACKGROUND

• Wuthisiri W, Peou C, Lekskul A, Chokthaweesak W. Maximal Levator Resection Beyond Whitnall's Ligament in Severe Simple Congenital Ptosis with Poor Levator Function. Clin Ophthalmol. 2022 Feb 17;16:441-452. doi: 10.2147/OPTH.S340781. eCollection 2022.

  PMID: 35210749 BACKGROUND

• Allard FD, Durairaj VD. Current techniques in surgical correction of congenital ptosis. Middle East Afr J Ophthalmol. 2010 Apr;17(2):129-33. doi: 10.4103/0974-9233.63073.

  PMID: 20616918 BACKGROUND

Study Officials

• Ahmed Mohamed Elshafei, Professor

  Minia University

  STUDY DIRECTOR

Central Study Contacts

Zamzam Mohamed Alham, Assistant lecturer

CONTACT

+201016909914; yassozoma2@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: April 3, 2025
• First Posted: May 16, 2025
• Study Start: July 1, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: May 16, 2025

Record last verified: 2025-04