NCT06971172

Brief Summary

To assess the therapeutic efficacy of low level laser therapy on oral pemphigus vulgaris patients.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 8, 2024

Completed
5 months until next milestone

First Posted

Study publicly available on registry

May 14, 2025

Completed
18 days until next milestone

Study Start

First participant enrolled

June 1, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2025

Completed
Last Updated

May 14, 2025

Status Verified

May 1, 2025

Enrollment Period

1 month

First QC Date

December 8, 2024

Last Update Submit

May 10, 2025

Conditions

Pemphigus Vulgaris

Outcome Measures

Primary Outcomes (1)

  • wound margins in millimeters

    Measurement

    1 month

Study Arms (2)

Low energy laser plus medical treatment

EXPERIMENTAL

Device

Device: Low energy diode Laser

Medical treatment

ACTIVE COMPARATOR

Medical treatment

Drug: Medication

Interventions

Low energy diode LaserDEVICE

Diode Laser

Low energy laser plus medical treatment
MedicationDRUG

pulse steriod therapy and immunosuppressive drugs

Medical treatment

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with oral pemphigus vulgaris

You may not qualify if:

  • other causes of oral ulcers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Pemphigus

Interventions

Dosage Forms

Condition Hierarchy (Ancestors)

Skin Diseases, VesiculobullousSkin DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Pharmaceutical PreparationsTechnology, PharmaceuticalInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
University doctor

Study Record Dates

First Submitted

December 8, 2024

First Posted

May 14, 2025

Study Start

June 1, 2025

Primary Completion

July 1, 2025

Study Completion

September 1, 2025

Last Updated

May 14, 2025

Record last verified: 2025-05