Key Insights

Highlights

Success Rate

60% trial completion

Published Results

11 trials with published results (33%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

24.2%

8 terminated out of 33 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

21%

7 trials in Phase 3/4

Results Transparency

92%

11 of 12 completed with results

Key Signals

11 with results60% success

Data Visualizations

Phase Distribution

27Total
Not Applicable (2)
P 1 (5)
P 2 (13)
P 3 (5)
P 4 (2)

Trial Status

Completed12
Terminated8
Unknown7
Recruiting4
Withdrawn1
Not Yet Recruiting1

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT02753777RecruitingPrimary

Autoimmune Blistering Diseases Study

NCT07461103Phase 2CompletedPrimary

Effect of Topical Insulin on Healing Rate of Pemphigus Lesions

NCT04422912Phase 1RecruitingPrimary

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

NCT05000216Phase 2Terminated

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

NCT06971172Not ApplicableNot Yet RecruitingPrimary

Low-level Laser Therapy on Oral Pemphigus Vulgaris Patients.

NCT04598477Phase 3TerminatedPrimary

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

NCT06846255Phase 4CompletedPrimary

Comparing DCP and DAP for Pemphigus Vulgaris

NCT04598451Phase 3CompletedPrimary

A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

NCT06581562Phase 1Recruiting

Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.

NCT05635266Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

NCT03239470Phase 1Terminated

Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus

NCT04540133Phase 2Completed

Dexamethasone Solution and Dexamethasone in Mucolox™

NCT06167408CompletedPrimary

Identifying Factors Influencing In-Hospital Relapse in Pemphigus Patients

NCT05338112UnknownPrimary

Role of Tzanck Smear in Determining Pemphigus Vulgaris Disease Activity

NCT02704429Phase 2CompletedPrimary

A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris

NCT05594472Phase 3UnknownPrimary

Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous Pemphigoid

NCT04096222UnknownPrimary

Comparative Analysis of the Th17 Cellular Response in Active and Inactive Pemphigus Vulgaris Patients

NCT05303272Phase 4UnknownPrimary

A Study to Evaluate Efficacy and Safety of Abatacept in Participants of Pemphigus Vulgaris (PV)

NCT01930175Phase 2TerminatedPrimary

Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris

NCT04023149Phase 2UnknownPrimary

Efficacy of Interleukin-2 Gargle in the Treatment of Oral Mucosa Lesion in Pemphigus Vulgaris

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