Causes of Secondary and Prolonged Fever During Treatment of Bacterial Meningitis and Viral Encephalitis

NCT06971133 | Not Yet Recruiting

• 1 other identifier: meningitis and encephalitis
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of the present study is to investigate causes of secondary and prolonged fever during treatment of viral encephalitis and bacterial meningitis in children aged from one month to 18 years .

Conditions

Meningitis in Children; Encephalitis in Children

Outcome Measures

Primary Outcomes (1)

• Causes of secondary and prolonged fever during treatment of bacterial meningitis and viral encephalitis

  Causes of secondary and prolonged fever during treatment of bacterial meningitis and viral encephalitis

  Basline

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Included children aged from one month to 18 years , who were diagnosed as bacterial meningitis or viral encephalitis and admitted to neurological department at AUCH and develop secondary or prolonged fever despite appropriate treatment .

You may qualify if:

• Children from one month to 18 years.
• Who were diagnosed with bacterial meningitis or viral encephalitis and admitted to neurological department at Assiut University Children's Hospital (AUCH).
• Develop secondary or prolonged fever despite appropriate treatment.

You may not qualify if:

• Pediatric patients with suspected autoimmune encephalitis.
• Patient on immunosuppressive therapy (e.g., post-organ transplant, chemotherapy).
• Pediatric patients suspected metabolic disorders.
• Those with suspected endocrine dysfunction.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Brouwer MC, McIntyre P, de Gans J, Prasad K, van de Beek D. Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev. 2010 Sep 8;(9):CD004405. doi: 10.1002/14651858.CD004405.pub3.

  PMID: 20824838 BACKGROUND

Study Officials

• Prof. Mostafa Shafeek Khalaf Tawfeek, Professor of Pediatrics

  Assiut University

  PRINCIPAL INVESTIGATOR

• Dr. Khalaf Abd El-Aal Sayed Mohamed, Lecturer of Pediatrics

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Kerolos Atef Shafeek Tanious

CONTACT

+201278046794; keroatef743@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: April 29, 2025
• First Posted: May 14, 2025
• Study Start: May 1, 2025
• Primary Completion: April 1, 2026
• Study Completion: May 1, 2026
• Last Updated: May 14, 2025

Record last verified: 2025-05