Relation Between Aortic Sclerosis &Severity of Coronary Heart Disease.

NCT06965218 | Not Yet Recruiting

• 1 other identifier: Soh-Med-25-4___1MD
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

the goal of the study to identify the relation between aortic valve sclerosis and severity of coronary heart disease by performing transthoracic echo Doppler study for severity of aortic valve sclerosis in patient will undergo coronary angiography with calculation of syntax score as a tool for severity of coronary heart disease.

Conditions

Aortic Valve Sclerosis

Outcome Measures

Primary Outcomes (1)

• relation between Aortic valve sclerosis and severity of coronary heart disease

  significant relation between severity of aortic valve sclerosis assessed by trans thoracic echo doppler quantified by Chandra et al on a scale of 0 to 3. 0 (no involvement). 1. mild (minor involvement of one leaflet) 2. moderate (minor involvement of two leaflets or extensive involvement of one leaflet. 3. severe (extensive involvement of two leaflets or involvement of all three leaflets). And severity of coronary heart disease in patients already underwent or planned to perform coronary angiography quantified by syntax score considering score above 20 as severe coronary heart disease.

  6 months

Interventions

Trans thoracic echo doppler DIAGNOSTIC_TEST

Aortic valve sclerosis severity study be transthoracic echo doppler

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

100a patients from both sex who are diagnosed to be aortic valve sclerosis and will undergo coronary angiography in Sohag university hospital

You may qualify if:

• Aortic sclerosis diagnosed by trans thoracic echo doppler

You may not qualify if:

• patients who known to be Rumatic heart disease or congenital aortic valve disease.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag faculty of medicine

Sohag, Egypt

Location

Central Study Contacts

Mohamed Ali shaker, MD

CONTACT

0021003474075; mohamed_ali_post@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: cardiologist

Study Record Dates

• First Submitted: April 24, 2025
• First Posted: May 11, 2025
• Study Start: May 1, 2025
• Primary Completion: November 1, 2025
• Study Completion: May 1, 2026
• Last Updated: May 11, 2025

Record last verified: 2025-05

Locations

EG (1)