Sustainable Implementation of the EXCEL Exercise Oncology Program Across Canada
EXCEL
1 other identifier
interventional
740
1 country
5
Brief Summary
EXCEL will provide online and, where feasible, in-person exercise programs to individuals living with and beyond cancer (ILWBC). Research has shown that targeted programs that include tailored exercise prescriptions are more successful in helping individuals with chronic disease to incorporate physical activity and exercise into their daily routines. While ILWBC are advised by healthcare professionals (HCPs) to engage in exercise, there is a lack of cancer-specific exercise programs and cancer-trained exercise specialists in Canada, outside of the research setting. Considering the negative impact cancer and its treatments have on fitness and physical activity levels, community-based efforts towards improving access, uptake and maintenance of exercise programming are needed. This study will evaluate the benefits of a community-based or online EXCEL exercise program for people living with and beyond cancer across Canada, using a streamlined intake process compared to the original EXCEL Study (HREBA.CC-20-0098, NCT04478851). This 8 to 12-week program (intervention) will be delivered in-person or over virtual platform. It includes twice weekly supervised exercise classes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable cancer
Started Mar 2025
5 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 11, 2025
CompletedFirst Submitted
Initial submission to the registry
April 4, 2025
CompletedFirst Posted
Study publicly available on registry
May 7, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 30, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 30, 2026
October 7, 2025
March 1, 2025
1.6 years
April 4, 2025
October 2, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Physical Activity Level
The Modified Godin Leisure Time Exercise Questionnaire is used to determine subjective levels of physical activity in each participant.
Baseline to one year
Secondary Outcomes (11)
Cancer related symptoms
Baseline to one year
Cost-effectiveness
Baseline to one year
Fatigue
Baseline to one year
Quality of life
Baseline to one year
Body Composition
Baseline to 12-weeks
- +6 more secondary outcomes
Study Arms (1)
Intervention
EXPERIMENTALAll participants will be involved in group exercise classes, twice a week for 8-12 weeks.
Interventions
Participants will take part in a combination of aerobic, resistance, balance, and flexibility exercises delivered in a circuit-type class setting, twice weekly for a 8-12-week period (duration of intervention depends on scheduling logistics for the coordinating hubs and their spokes sites). The exercise sessions will be conducted in groups with a ratio of up to 15 participants per instructor. The program follows exercise progression principles (i.e., frequency, intensity, time, type, overload and progression) over the 8-12-weeks, with tailoring of any exercise to meet individual participant needs as required, in order to promote fitness and wellness benefits.
Eligibility Criteria
You may qualify if:
- have or had a diagnosis of cancer;
- be 18 years or older;
- be able to participate in low-intensity levels of activity, at minimum;
- be pretreatment, or receiving active cancer treatment (i.e., surgery, systemic therapy and radiation therapy), have received cancer treatment within the past 3 years, or if beyond 3 years since treatment completion, have a referral from their healthcare team indicating they have side effects from cancer treatment or the cancer itself, that could be improved or managed with exercise;
- be able to provide informed written consent in English or French
You may not qualify if:
- does not or did not have a cancer diagnosis
- is under the age of 18
- is unable to participate in mild exercise, at minimum
- is not pretreatment, or receiving active cancer treatment (i.e., surgery, systemic therapy and radiation therapy), has not received cancer treatment within the past 3 years, or if beyond 3 years since treatment completion, doesn't have side effects from cancer treatment or the cancer itself, that could be improved or managed with exercise
- unable to read/write in English
- for online programs, does not have internet or computer access
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Calgarylead
- University of Albertacollaborator
- Dalhousie Universitycollaborator
- Nova Scotia Health Authoritycollaborator
- University of Torontocollaborator
- Centre hospitalier de l'Université de Montréal (CHUM)collaborator
- University of British Columbiacollaborator
- Memorial University of Newfoundlandcollaborator
- University of Prince Edward Islandcollaborator
- Alberta Health servicescollaborator
Study Sites (5)
University of Calgary
Calgary, Alberta, T2N1N4, Canada
University of British Columbia
Vancouver, British Columbia, V6T 1Z7, Canada
Nova Scotia Health Authority
Halifax, Nova Scotia, B3H 4R2, Canada
University of Toronto
Toronto, Ontario, M5S 1A1, Canada
Centre hospitalier de l'Université de Montréal
Montreal, Quebec, H2X 0A9, Canada
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nicole Culos-Reed, PhD
University of Calgary
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 4, 2025
First Posted
May 7, 2025
Study Start
March 11, 2025
Primary Completion (Estimated)
October 30, 2026
Study Completion (Estimated)
November 30, 2026
Last Updated
October 7, 2025
Record last verified: 2025-03
Data Sharing
- IPD Sharing
- Will not share
No plan at this time to share IPD outside of the research team.