NCT05549479

Brief Summary

Background: By 2030, 23% of Canadians will be over 65 years of age. Two in five of these individuals will be diagnosed with cancer. Older adults have high levels of functional decline, and a cancer diagnosis adds prolonged physical sequelae to the natural aging process. Many of these effects can be mitigated by regular exercise. However, older adult cancer survivors are significantly less likely to meet current exercise guidelines than their younger counterparts. As our population ages, we need to develop effective, scalable interventions that support health in older adult cancer survivors. The objective of this study is to determine the feasibility and preliminary effectiveness of a virtually delivered peer exercise intervention with qualified exercise professional (QEP) support for older adult cancer survivors. Methods: Participants will include older adult cancer survivors who are cleared for exercise, have consistent access to the internet, and currently take part in less than 150 minutes of exercise per week. All participants will be matched with a partner, given a peer support guide, and information on current exercise guidelines. In addition to being matched with a peer, dyads in the intervention group will have weekly virtual sessions with a QEP for 10 weeks. Participants in the control group will independently support their partner around exercise for 10 weeks. Outcomes: Participants will be assessed at 3 time points. The primary outcome is feasibility. This will be measured by assessing recruitment, retention, adherence rates to the intervention, and participant acceptability and satisfaction. Secondary effectiveness outcomes include exercise volume, social support, quality of life, physical function, and physical activity enjoyment. Impact: If effective, this will be the first virtual peer-based exercise intervention for older adult cancer survivors. Findings will inform future methods aimed at increasing exercise in older adults.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable cancer

Timeline
Completed

Started Dec 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 23, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

September 22, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2022

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2024

Completed
Last Updated

February 21, 2025

Status Verified

January 1, 2025

Enrollment Period

1.9 years

First QC Date

August 23, 2022

Last Update Submit

February 20, 2025

Conditions

Outcome Measures

Primary Outcomes (4)

  • Recruitment rate

    The percentage of eligible individuals who expressed interest in the study that enrolled

    10 weeks

  • Retention rate

    The percentage of enrolled participants who completed the intervention

    10 weeks

  • Adherence rate

    The percentage of total sessions attended and tracked using weekly logs

    10 weeks

  • Participant Satisfaction

    7 points Likert satisfaction scale

    10 weeks

Secondary Outcomes (16)

  • Exercise volume

    10 weeks

  • Exercise volume

    14 weeks

  • Exercise volume

    10 weeks

  • Exercise volume

    14 weeks

  • Social support

    10 weeks

  • +11 more secondary outcomes

Study Arms (2)

Intervention Group (AgeMatchPLUS).

EXPERIMENTAL
Behavioral: Peer MatchingBehavioral: Qualified Exercise Professional Support Sessions

Control Condition (AgeMatch):

ACTIVE COMPARATOR
Behavioral: Peer Matching

Interventions

Peer MatchingBEHAVIORAL

Participants will be matched with a peer based on evidence informed criteria. Partners will independently communicate and support each other around exercise for the duration of the study.

Control Condition (AgeMatch):Intervention Group (AgeMatchPLUS).

Dyads will participate in weekly virtual sessions with a QEP for 10 weeks. Each session will last up to 1 hour. The QEP (i.e., registered kinesiologist) will provide a tailored exercise program, focusing on aerobic activity for both individuals in the dyad based on personal circumstances, cancer-related characteristics, side effects, current fitness level (consistent with home-based exercise strategies), and personal preferences.

Intervention Group (AgeMatchPLUS).

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English speaking
  • Older adult (\>60 years)
  • Living with or beyond a cancer diagnosis (any type or stage of cancer at any stage of treatment)
  • Living in Canada
  • Medically cleared for exercise
  • Have consistent access to an internet-connected device with webcam
  • Currently take part in less than 150 minutes of MVPA per week

You may not qualify if:

  • Self-report any contraindications to exercise
  • Had recent (in the last 4 weeks) or have planned surgery of any kind (including reconstructive surgery) in the next 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

McMaster University

Hamilton, Ontario, L8S1C7, Canada

Location

Related Publications (1)

  • Smith-Turchyn J, Sinclair S, O'Loughlin EK, Innes A, Vani MF, Beauchamp M, Phillips SM, Richardson J, Thabane L, Sabiston CM. A pilot randomized controlled trial of a virtual peer-support exercise intervention for female older adults with cancer. BMC Geriatr. 2024 Oct 26;24(1):887. doi: 10.1186/s12877-024-05495-z.

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 23, 2022

First Posted

September 22, 2022

Study Start

December 1, 2022

Primary Completion

October 15, 2024

Study Completion

October 15, 2024

Last Updated

February 21, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share

Locations