NCT06957587

Brief Summary

  1. 1.Background \& Rationale:
  2. 2.Objective:
  3. 3.Study Design:
  4. 4.Methods:
  5. 5.Expected Outcome \& Significance:

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
800

participants targeted

Target at P75+ for all trials

Timeline
16mo left

Started Oct 2025

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress31%
Oct 2025Aug 2027

First Submitted

Initial submission to the registry

April 26, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 4, 2025

Completed
5 months until next milestone

Study Start

First participant enrolled

October 1, 2025

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2027

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2027

Last Updated

November 17, 2025

Status Verified

November 1, 2025

Enrollment Period

1.8 years

First QC Date

April 26, 2025

Last Update Submit

November 13, 2025

Conditions

Blood Volume AnalysisUltrasoundMachine Learning

Outcome Measures

Primary Outcomes (1)

  • Quantitative estimation of blood volume

    We will estimate the basic blood volume of the patients quantitatively with the Acute Hemodilution technique before the surgery.

    within 30mins before the surgery

Study Arms (1)

patients prepare to receive surgery

The patients aged 18-75 years old prepare to receive surgery will be assigned into the cohort.

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients prepare to receive surgery.

You may qualify if:

  • Agree to join this study and sign the informed consent form;
  • Age between 18 and 75 years old (inclusive);
  • BMI (body mass index) is between 18 and 30 kg/m2;
  • American Society of Anesthesiologists (ASA) grades I-II

You may not qualify if:

  • Preoperative hemoglobin (Hb) \<10g/dl
  • Cardiac dysfunction (NYHA class III-IV), respiratory dysfunction (ATS class 2-4), history of liver and kidney dysfunction (such as transaminase / albumin / bilirubin abnormalities, hepatitis history, serum creatinine / urea nitrogen rise, etc.), nervous system abnormalities (those who cannot cooperate due to stroke or its sequelae, Alzheimer, etc.);
  • The ultrasonic display of inferior vena cava, internal jugular vein, subclavian vein or common carotid artery is extremely poor, venous thrombosis or anatomical abnormalities;
  • Multiple injury with chest, abdomen or brain;
  • Pregnant woman

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Shanghai, Shanghai Municipality, 200235, China

NOT YET RECRUITING

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Shanghai, Shanghai Municipality, 200235, China

RECRUITING

Central Study Contacts

xiuxiu sun, MD

CONTACT

021-64369181liuyuanec@163.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
attending doctor

Study Record Dates

First Submitted

April 26, 2025

First Posted

May 4, 2025

Study Start

October 1, 2025

Primary Completion (Estimated)

July 31, 2027

Study Completion (Estimated)

August 31, 2027

Last Updated

November 17, 2025

Record last verified: 2025-11

Locations

CN(2)