NCT05849909

Brief Summary

Evaluation of carotid plaque vulnerability based on ultrasound imaging features， proteomics and metabolomics: a clinical multicenter study

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
57

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 18, 2023

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 20, 2023

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

April 28, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 9, 2023

Completed
12 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 18, 2024

Completed
Last Updated

May 9, 2023

Status Verified

April 1, 2023

Enrollment Period

2 days

First QC Date

April 28, 2023

Last Update Submit

April 28, 2023

Conditions

Ultrasound

Outcome Measures

Primary Outcomes (1)

  • ultrasound

    B mode

    2023.05

Study Arms (2)

Stable Carotid Atherosclerotic Plaques

Unstable Carotid Atherosclerotic Plaques

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients undergoing carotid endarterectomy

You may qualify if:

  • Patients who meet the CEA surgical indications;
  • Age\>18 years old;
  • Patients who sign informed consent forms

You may not qualify if:

  • Those with severe calcification of plaques and obvious acoustic shadows, and poor image quality;
  • Contraindications to ultrasound contrast, such as those who are allergic to contrast agents;
  • Intracardiac right to left shunt;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Ultrasound, Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, 310000, China

RECRUITING

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Director of Ultrasound Department

Study Record Dates

First Submitted

April 28, 2023

First Posted

May 9, 2023

Study Start

April 18, 2023

Primary Completion

April 20, 2023

Study Completion

April 18, 2024

Last Updated

May 9, 2023

Record last verified: 2023-04

Locations

CN(1)