Functional Status in Hospitalized Endocrine Disorders

NCT06952244 | Enrolling By Invitation

• 1 other identifier: 561-561-10
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this observational study was to examine the clinical and functional characteristics of patients hospitalized in the endocrinology department of a university hospital. In line with this purpose, the following research questions were given. What are the respiratory functions and respiratory rates of patients hospitalized in the endocrinology department? What are the muscle strengths of patients hospitalized in the endocrinology department? What is the general health status of patients hospitalized in the endocrinology department? What is the quality of life of patients hospitalized in the endocrinology department? What is the fatigue status of patients hospitalized in the endocrinology department? What is the level of independence of patients hospitalized in daily living activities of patients hospitalized in the endocrinology department? What are the routine blood values of patients hospitalized in the endocrinology department? What is the sleep quality of patients hospitalized in the endocrinology department? What are the physical activity levels of patients hospitalized in the endocrinology department? What is the balance status of patients hospitalized in the endocrinology department? What is the neuropathic pain status of patients hospitalized in the endocrinology department? The patients hospitalized in the Endocrinology Department of Uşak Education and Research Hospital constitute the sample of the study. Clinical and functional evaluations will be made from the participants during their hospital stay. In this context, respiration, muscle strength, general pain assessment, life expectancy, fatigue, independence levels, sleep quality, routine blood values, physical activity levels, balance status and neuropathic status evaluation will be made.

Conditions

Endocrine Diseases; Hospitalized

Keywords

endocrine diseases; functional assessment; clinical assesment; Hospitalization; Individuals with endocrine disorders

Outcome Measures

Primary Outcomes (12)

• Assessment of respiratory functions

  Respiratory rate: Respiratory rate provides important information in the diagnosis of respiratory problems and in the evaluation of the general health status of the individual. The number of breaths the individual takes in a minute (how many times the chest rises) will be counted. During the evaluation, the hands will be placed on the patient's chest and the movements in the chest wall will be felt and the counts made during rest, inspiration and expiration will be evaluated.

  At the time of enrollment

• Chest circumference measurement

  Chest circumference measurement: Respiratory function is an important parameter for monitoring and evaluating respiratory functions. The measurement will be taken at the level of the fourth rib, where the lower end of the scapula passes, while standing with the arms abducted. The measurement will be made twice during rest, inspiration and expiration. Thus, chest mobility will also be evaluated.

  At the time of enrollment

• Assessment of muscle strength

  Manual Muscle Testing: Manual muscle testing is used to assess the muscle strength of individuals and identify possible weaknesses or imbalances. The strength of large muscle groups such as quadriceps femoris and biceps brachii is essential for individuals to carry out their daily activities. Weakness in these muscles can negatively affect a person's independence and quality of life. In our study, muscle strength will be assessed with a score between 0 and 5 (0: no muscle contraction is felt, 5: full movement of the segment against gravity and with maximum resistance).

  At the time of enrollment

• Pain assessment

  Pain assessment will be done with Visual Analog Scale (VAS). VAS includes a scale with a starting and ending point on a line to evaluate a specific feature. Individuals evaluate the severity of their condition by placing a mark on this line. In this scale, 0 represents the absence of a specific feature or no sensation, and 10 represents the highest intensity of that feature. In our study, it was used to evaluate general health status.

  At the time of enrollment

• Quality of life assessment

  Short Form-36 Health Survey (SF-36) was developed by John E. Ware and colleagues (1992) to measure health-related quality of life. It consists of a total of 36 questions covering physical, psychological and social dimensions. Sub-dimensions: Physical Function, Social Function, Body Pain, General Health, Mental Health, Vitality, Physical Role and Emotional Role. Scores calculated for each subscale range from 0 to 100, where higher scores indicate better health status, functioning and quality of life.

  At the time of enrollment

• Fatigue assessment

  Functional Assessment of Chronic Illness Therapy (FACIT): FACIT is a scale developed to assess the level of fatigue that individuals experience, particularly due to chronic diseases. This scale, consisting of a total of 13 questions, measures the level of fatigue and energy experienced by individuals in the last week. Each item on the FACIT scale is scored between 0 and 4; responses range from "never" to "very often." The total score obtained ranges from 0 to 52, with higher scores indicating lower fatigue and better quality of life.

  At the time of enrollment

• Assessing their independence in activities of daily living

  Assessment of independence in daily living activitiesBarthel Index: It will be assessed with the Barthel Index. The Barthel index was developed by Florence I. Mahoney and Dorothy W. Barthel in 1965. It is used to assess the level of independence in daily living activities. Scoring: Scored between 0-100. Higher scores mean more independence. The areas of use of this index are rehabilitation, post-stroke independence assessment, neurological and geriatric patients. It is a short and easy-to-use index.

  At the time of enrollment

• Routine Blood Values Examination

  Routine blood tests consist of standard biochemistry, hemogram, and electrolyte tests that evaluate the general health status of the individual. This assessment was not developed by any specific author; it is standardized by medical guidelines and laboratory practices.

  At the time of enrollment

• Evaluation of sleep quality

  PSQI (Pittsburgh Sleep Quality Index): PSQI was developed by Daniel J. Buysse and colleagues (1989). It is used to evaluate sleep quality and sleep disorders. Sub-dimensions: Subjective Sleep Quality, Sleep Latency (Time to Fall Asleep), Sleep Duration, Sleep Efficiency, Sleep Disorders, Medication Use, Daytime Functioning. Scoring: Scored between 0-21; 5 and above indicates poor sleep quality.

  At the time of enrollment

• The physical activity level

  The physical activity level will be assessed. The International Physical Activity Questionnaire (IPAQ) was developed by the World Health Organization and an international consortium. It is a standard tool for assessing physical activity level. This questionnaire was developed by Craig et al. (2003). The scale has 3 categories. These are: Categories: Low Activity, Moderate Activity, High Activity. It is a questionnaire frequently used in studies related to sports sciences, public health and physical activity level.

  At the time of enrollment

• Balance assessment

  Balance assessment will be evaluated with the Berg Balance Scale. The Berg Balance Scale was developed by Katherine Berg and her colleagues in 1992. The Berg Balance Scale is a clinical assessment tool used to assess individuals' risk of falling, measure functional balance levels, and monitor the effectiveness of rehabilitation programs. Total Number of Items on the Scale: 14 items. Scoring: Each item is scored between 0 and 4 (0 = cannot perform the task, 4 = performs the task completely). Total Score Range: 0-56.

  At the time of enrollment

• Neuropathy evaluation

  Neuropathy assessment will be done with the Michigan Neuropathy Assessment Questionnaire. The Michigan Neuropathy Assessment Questionnaire was developed by William H. Herman and colleagues (1994). It is used to assess diabetic neuropathy. The questionnaire asks about the patient's neuropathy symptoms (tingling, numbness, pain in the feet, etc.). Clinical assessment findings such as tenderness in the feet, loss of reflexes, and thinning of the skin will be examined.

  At the time of enrollment

Study Arms (1)

Patients hospitalized in the endocrinology ward

patients in the endocrinology service will be accepted to Uşak training and research hospital with a doctor's diagnosis. General physical, functional and psychosocial and blood values evaluations will be made.

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The sample of the study consists of patients aged between 18-64 years who are hospitalized in the Endocrinology Department of Uşak Training and Research Hospital.

You may qualify if:

• Being between the ages of 18-64
• Being a volunteer
• Being hospitalized in the endocrinology ward.

You may not qualify if:

• Patients who have any obstacles to participating in surveys and measurements,
• Patients with missing data for any reason, and patients who are not accepted to the endocrinology service

Sponsors & Collaborators

• Uşak University: lead

Study Sites (1)

Uşak Education and Research Hospital

Uşak, Uşak, 64000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Endocrine System Diseases

Study Officials

• Kevser Gursan, Dr.

  Uşak University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 20, 2025
• First Posted: April 30, 2025
• Study Start: April 15, 2025
• Primary Completion: August 15, 2025
• Study Completion: August 15, 2025
• Last Updated: April 30, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)