NCT06952049

Brief Summary

This project is a single-site, five-arm, randomized controlled trial investigating whether providing patients in an orthopedic clinic waiting room psychoeducation about mindfulness impacts the degree of pain relief they experience during a mindfulness-based intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
646

participants targeted

Target at P75+ for not_applicable pain

Timeline
Completed

Started Apr 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 10, 2025

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

April 23, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 30, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 18, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 18, 2025

Completed
Last Updated

February 27, 2026

Status Verified

August 1, 2025

Enrollment Period

8 months

First QC Date

April 23, 2025

Last Update Submit

February 25, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Pain Unpleasantness Numeric Rating Scale

    Change in acute pain unpleasantness will be measured with an individual item ("How unpleasant is your pain, right now?") rated on a numeric rating scale. Scores range from 0 to 10, with higher scores reflecting greater acute pain unpleasantness.

    Immediately before to after 3-minute audio recording

Secondary Outcomes (2)

  • Change in Pain Intensity Numeric Rating Scale

    Immediately before to after 3-minute audio recording

  • Change in Anxiety Numeric Rating Scale

    Immediately before to after 3-minute audio recording

Study Arms (5)

Pain Psychoeducation

ACTIVE COMPARATOR

In the pain psychoeducation intervention, participants will be randomized to listen to a three-minute recording about different pain management strategies (e.g., ice, rest) to promote overall well-being.

Behavioral: Pain Psychoeducation

Mindfulness without Psychoeducation

EXPERIMENTAL

In the mindfulness without psychoeducation intervention, participants will be randomized to listen to a three-minute mindfulness practice consisting of 1 minute of mindful breathing, 1 minute of mindful mapping, and 1 minute of mindfulness of personal meaning.

Behavioral: Mindfulness without Psychoeducation

1 Minute Psychoeducation with 2 Minutes of Mindfulness (Pain Focus)

EXPERIMENTAL

In the 1 Minute Psychoeducation with 2 minutes of Mindfulness (Pain Focus) intervention, participants will be randomized to listen to a 1 minute of psychoeducation about mindfulness, 1 minute of mindful breathing and 1 minute of mindful mapping.

Behavioral: 1 Minute Psychoeducation with 2 Minutes of Mindfulness (Pain Focus)

1 Minute Psychoeducation with 2 Minutes of Mindfulness (Meaning Focus)

EXPERIMENTAL

In the 1 Minute Psychoeducation with 2 minutes of Mindfulness (Meaning Focus) intervention, participants will be randomized to listen to a 1 minute of psychoeducation about mindfulness, 1 minute of mindful breathing and 1 minute of mindfulness of personal meaning.

Behavioral: 1 Minute Psychoeducation with 2 Minutes of Mindfulness (Meaning Focus)

2 Minutes of Psychoeducation with 1 Minute of Mindfulness

EXPERIMENTAL

In the 2 Minutes of Psychoeducation with 1 Minute of Mindfulness intervention, participants will be randomized to listen to a 2 minute of psychoeducation about mindfulness and 1 minute of mindful breathing.

Behavioral: 2 Minutes of Psychoeducation with 1 Minute of Mindfulness

Interventions

In the pain psychoeducation intervention, participants will be randomized to listen to a three-minute recording about different pain management strategies (e.g., ice, rest) to promote overall well-being.

Pain Psychoeducation

In the mindfulness without psychoeducation intervention, participants will be randomized to listen to a three-minute mindfulness practice consisting of 1 minute of mindful breathing, 1 minute of mindful mapping, and 1 minute of mindfulness of personal meaning.

Mindfulness without Psychoeducation

In the 1 Minute Psychoeducation with 2 minutes of Mindfulness (Pain Focus) intervention, participants will be randomized to listen to a 1 minute of psychoeducation about mindfulness, 1 minute of mindful breathing and 1 minute of mindful mapping.

1 Minute Psychoeducation with 2 Minutes of Mindfulness (Pain Focus)

In the 1 Minute Psychoeducation with 2 minutes of Mindfulness (Meaning Focus) intervention, participants will be randomized to listen to a 1 minute of psychoeducation about mindfulness, 1 minute of mindful breathing and 1 minute of mindfulness of personal meaning.

1 Minute Psychoeducation with 2 Minutes of Mindfulness (Meaning Focus)

In the 2 Minutes of Psychoeducation with 1 Minute of Mindfulness intervention, participants will be randomized to listen to a 2 minute of psychoeducation about mindfulness and 1 minute of mindful breathing.

2 Minutes of Psychoeducation with 1 Minute of Mindfulness

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Receiving pain treatment at Tallahassee Orthopedic Center
  • Understanding English instructions fluently
  • Being 18 years of age or older

You may not qualify if:

  • Unable to consent because of physical or mental incapacity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tallahassee Orthopedic Clinic (TOC)

Tallahassee, Florida, 32308, United States

Location

MeSH Terms

Conditions

PainAcute Pain

Interventions

Mindfulness

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Cognitive Behavioral TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 23, 2025

First Posted

April 30, 2025

Study Start

April 10, 2025

Primary Completion

December 18, 2025

Study Completion

December 18, 2025

Last Updated

February 27, 2026

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations