NCT06949709

Brief Summary

The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 4, 2024

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 27, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 27, 2024

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

April 22, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 29, 2025

Completed
Last Updated

May 2, 2025

Status Verified

April 1, 2025

Enrollment Period

8 months

First QC Date

April 22, 2025

Last Update Submit

April 29, 2025

Conditions

Glucose LevelsLipid ProfileSubstrate OxidationBlood PressureInsulin Sensitivity

Keywords

Fasted-exerciseGlucose controlLipid oxidation

Outcome Measures

Primary Outcomes (2)

  • Glucose responses

    Changes in glucose concentrations between trials

    375 minutes

  • Insulin responses

    Changes in insulin concentrations between trials

    375 minutes

Secondary Outcomes (5)

  • Triacylglycerol responses

    375 minutes

  • Blood pressure

    375 minutes

  • Heart rate variability (HRV)

    375 minutes

  • Cognitive function

    375 minutes

  • Visual Analog Scales (VAS)

    375 minutes

Study Arms (2)

Fasted-exercise

EXPERIMENTAL

Breakfast intake before 30 min walking

Behavioral: Fasted-exercise

Fed-exercise

EXPERIMENTAL

30 min walking before breakfast intake

Behavioral: Fed-exercise

Interventions

Fasted-exerciseBEHAVIORAL

Breakfast intake before 30 min brisk walking on a treadmill

Fasted-exercise
Fed-exerciseBEHAVIORAL

30 min brisk walking on a treadmill before breakfast intake

Fed-exercise

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 20 and 45 years
  • Regular walking habit of at least 7500 steps per day
  • Engage in continuous walking for at least 20 minutes on 2 or more days per week
  • Body Mass Index (BMI) ranging from 18.5 to 27 kg/m2
  • No habits of heavy drinking or smoking, or have quit smoking for at least 6 months
  • Absence of diabetes, cardiovascular, or metabolic-related disorders
  • Not currently taking prescription drugs, over-the-counter medications, or other supplements that may affect blood sugar, blood pressure, or metabolic changes
  • No current sports injuries or medical advice against exercise
  • No significant weight fluctuations in the past three months (within ±3% of usual body weight)
  • Not experiencing shift work or travel across time zones within the past six months
  • No current plans to change lifestyle habits and willing to adhere to the requirements of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan Normal University

Taipei, Taiwan

Location

MeSH Terms

Conditions

Insulin Resistance

Condition Hierarchy (Ancestors)

HyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 22, 2025

First Posted

April 29, 2025

Study Start

April 4, 2024

Primary Completion

November 27, 2024

Study Completion

November 27, 2024

Last Updated

May 2, 2025

Record last verified: 2025-04

Locations

TW(1)