Evaluating the Impact of WHO Trauma Care Checklist on Clinical Outcome of Patients

NCT06944340 | Completed

• 1 other identifier: 526/DME/KMC
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study is being conducted at the Department of Trauma and Orthopedics at Khyber Teaching Hospital, Peshawar. It will test whether using the World Health Organization (WHO) Trauma Care Checklist can help improve the care and recovery of patients who have experienced physical injuries (trauma). Injuries are a major cause of death and disability, especially in countries like Pakistan. When someone is seriously injured, doctors must act quickly and carefully to save lives and prevent long-term problems. Checklists are simple tools that help healthcare providers make sure nothing is missed during treatment. In this study, adult trauma patients will be randomly divided into two groups: One group will receive the standard trauma care (Group A). The other group will receive trauma care with the help of the WHO checklist (Group B). Doctors will compare the outcomes of both groups by looking at things like pain levels, injury severity, recovery progress, complications (like infections or organ problems), and overall satisfaction. The goal is to see if the checklist makes a meaningful difference in patient recovery and safety.

Conditions

Trauma Related Injuries; Trauma

Keywords

Trauma; Trauma Outcomes; WHO Trauma Care Checklist; Trauma Checklist; Injury; Emergency Care

Outcome Measures

Primary Outcomes (3)

• Improvement in Injury Severity Score (ISS)

  difference in ISS at admission and after initial management. A higher difference means a better outcome.

  Assessed at admission and after initial management.

• Glasgow Coma Scale (GCS) Score

  Consciousness levels of participant. Average change/rise/fall. Higher GCS means better outcome

  Measured at presentation and 1 hour post-treatment.

• level of Pain

  Pain levels using the Visual Analogue Scale (VAS). A lower VAS score means better outcome.

  Assessed after initial management.

Secondary Outcomes (5)

• All-Cause Mortality Rate

  1 month post-treatment.

• Incidence of Post-Trauma Complications

  1 month post-treatment

• Number of Bed-Bound Days

  From admission to discharge (up to 1 month)

• Patient Satisfaction Score

  Assessed at 1 month follow-up.

• Rate of Missed Injuries

  Identified during 1-month follow-up.

Study Arms (2)

Standard Trauma Care

NO INTERVENTION

Patients receive routine trauma care adhering to the hospital's existing protocols without using the WHO Trauma Care Checklist. Treatment includes stabilization, diagnostics, surgical/non-surgical interventions, and post-operative care as per institutional standards.

WHO Trauma Care Checklist-Guided Care

EXPERIMENTAL

Patients receive trauma care guided by the WHO Trauma Care Checklist. The checklist is systematically applied by trained clinicians at critical stages of care (e.g., admission, pre-operative, post-operative, and discharge phases) to ensure adherence to evidence-based practices, including airway management, hemorrhage control, infection prevention, and monitoring for complications.

Other: WHO Trauma Care Checklist

Interventions

WHO Trauma Care Checklist OTHER

A standardized checklist developed by the WHO for trauma care, designed to reduce errors and ensure compliance with critical steps in trauma management. Implemented by trained clinicians during patient assessment and treatment phases. Components include verification of patient identity, assessment of airway/breathing/circulation, pain management, monitoring for missed injuries, and post-resuscitation care. Checklist use is documented in medical records.

WHO Trauma Care Checklist-Guided Care

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 18 and 60 years old
• Glasgow Coma Scale (GCC) equal to or more than 10
• Consenting to participate in the study

You may not qualify if:

• Patients who refrain from continuing the study
• Patients with the incomplete checklist
• Pregnancy
• History of chronic mental illness, lung or kidney disease
• Undergoing chemotherapy.
• Illicit drug dependency

Sponsors & Collaborators

• Khyber Teaching Hospital: lead

Study Sites (1)

Emergency Department, Khyber Teaching Hospital

Peshawar, KPK, 25000, Pakistan

Location

Related Publications (2)

• Hyder AA, Razzak JA. The challenges of injuries and trauma in Pakistan: an opportunity for concerted action. Public Health. 2013 Aug;127(8):699-703. doi: 10.1016/j.puhe.2012.12.020. Epub 2013 Mar 13.

  PMID: 23489711 BACKGROUND

• Bidhendi S, Ahmadi A, Fouladinejad M, Bazargan-Hejazi S. Evaluating implementation of WHO Trauma Care Checklist vs. modified WHO checklist in improving trauma patient clinical outcomes and satisfaction. J Inj Violence Res. 2021 Jan;13(1):5-12. doi: 10.5249/jivr.v13i1.1579. Epub 2020 Aug 16.

  PMID: 32868497 BACKGROUND

MeSH Terms

Conditions

Wounds and Injuries

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Trainee Medical Officer

Model Details: Two-group, single-blinded, parallel assignment randomized controlled trial. Patients are randomly allocated to either receive standard trauma care (control group) or standard care enhanced with the WHO Trauma Care Checklist (intervention group). Outcomes are compared between groups over a 1-month follow-up period.

Study Record Dates

• First Submitted: April 15, 2025
• First Posted: April 25, 2025
• Study Start: April 26, 2025
• Primary Completion: August 15, 2025
• Study Completion: September 1, 2025
• Last Updated: September 17, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)