NCT06941285

Brief Summary

We assessed Montreal Cognitive Assessment scores before and after MRI guided focused ultrasound thalamotomy for tremor in order to identify if there are changes in cognitive function following treatment.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
142

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2013

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
10.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2024

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

April 16, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 23, 2025

Completed
Last Updated

April 23, 2025

Status Verified

April 1, 2025

Enrollment Period

10.6 years

First QC Date

April 16, 2025

Last Update Submit

April 16, 2025

Conditions

Essential Tremor

Outcome Measures

Primary Outcomes (1)

  • Montreal Cognitive Assessment

    Cognitive assessessment with higher score indicating better cognitive state

    baselin, preprocedure, 6 months and 1 year

Interventions

Data collectionOTHER

Data collection

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients that underwent MRI guided focused ultrasound thalamotomy and suffered from Essential tremor.

You may qualify if:

  • Patients that underwent MRI guided focused ultrasound thalamotomy and suffered from Essential tremor.

You may not qualify if:

  • Patients that did not undergo MRI guided focused ultrasound thalamotomy
  • Patinets that did not suffer from Essential tremor.
  • Patients that underwent MRI guided focused ultrasound for areas other then a thalamus
  • Patients tat underwent bilateral thalamothomy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Essential Tremor

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Movement DisordersCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Officials

  • Inna Senderova

    Rambam Health Care Campus

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director Movement Disorders Institute

Study Record Dates

First Submitted

April 16, 2025

First Posted

April 23, 2025

Study Start

November 1, 2013

Primary Completion

June 1, 2024

Study Completion

June 1, 2024

Last Updated

April 23, 2025

Record last verified: 2025-04