Urinary Incontinence After Endoscopic Prostatectomy

NCT06939140 | Completed

• 1 other identifier: UI after prostatectomy
• Study Type: observational
• Target: 133
• Locations: 1 country
• Sites: 1

Brief Summary

This is a prospective cohort study aiming to identify the preoperative and intraoperative predictors of urinary incontinence after endoscopic transurethral bipolar prostatectomy

Conditions

Urinary Incontinence (UI)

Keywords

Stress Urinary Incontinence (SUI); Urge Urinary Incontinence (UUI); Benign Prostatic Hyperplasia (BPH); Bipolar enucleation of the Prostate (BipolEP); Bipolar transurethral reaction of the prostate (B-TURP)

Outcome Measures

Primary Outcomes (1)

• Preoperative predictors of urinary incontinence

  Association between patients' preoperative parameters and occurrence of urinary incontinence after the procedure

  At 6 months after the procedure

Secondary Outcomes (1)

• Intraoperative predictors of urinary incontinence

  At 6 months after the procedure

Study Arms (1)

Endoscopic transurethral bipolar prostatectomy patients

Benign Prostatic Hyperplasia patients who will undergo endoscopic transurethral bipolar prostatectomy

Procedure: Bipolar prostatectomy

Interventions

Bipolar prostatectomy PROCEDURE

Endoscopic transurethral bipolar enucleation or reaction of the prostate

Endoscopic transurethral bipolar prostatectomy patients

Eligibility Criteria

• Age: 50 Years+
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Benign prostatic hyperplasia patients who will undergo endoscopic bipolar transurethral prostatectomy and develop urinary incontinence will be included in the study. Their preoperative and intraoperative data will be studied to identify if there is association between their preoperative and intraoperative parameters and the development of urinary incontinence after endoscopic bipolar transurethral prostatectomy

You may qualify if:

• Males ≥50 years undergoing primary B-TURP/BipolEP for BPH
• Preoperative IPSS ≥8, Qmax ≤15 mL/s, prostate volume ≥30mL
• No prior incontinence/neurological bladder dysfunction

You may not qualify if:

• Prostate cancer history
• Concurrent anti-incontinence procedures

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University Urology Hospital

Asyut, Egypt

Location

Related Publications (8)

• Matsushita K, Kent MT, Vickers AJ, von Bodman C, Bernstein M, Touijer KA, Coleman JA, Laudone VT, Scardino PT, Eastham JA, Akin O, Sandhu JS. Preoperative predictive model of recovery of urinary continence after radical prostatectomy. BJU Int. 2015 Oct;116(4):577-83. doi: 10.1111/bju.13087. Epub 2015 Mar 30.

  PMID: 25682782 BACKGROUND

• Castellani D, Rubilotta E, Fabiani A, Maggi M, Wroclawski ML, Teoh JY, Pirola GM, Gubbiotti M, Pavia MP, Gomez-Sancha F, Galosi AB, Gauhar V. Correlation Between Transurethral Interventions and Their Influence on Type and Duration of Postoperative Urinary Incontinence: Results from a Systematic Review and Meta-Analysis of Comparative Studies. J Endourol. 2022 Oct;36(10):1331-1347. doi: 10.1089/end.2022.0222. Epub 2022 Jun 13.

  PMID: 35587146 BACKGROUND

• Bauer RM, Gozzi C, Hubner W, Nitti VW, Novara G, Peterson A, Sandhu JS, Stief CG. Contemporary management of postprostatectomy incontinence. Eur Urol. 2011 Jun;59(6):985-96. doi: 10.1016/j.eururo.2011.03.020. Epub 2011 Mar 21.

  PMID: 21458914 BACKGROUND

• Sandhu JS, Breyer B, Comiter C, Eastham JA, Gomez C, Kirages DJ, Kittle C, Lucioni A, Nitti VW, Stoffel JT, Westney OL, Murad MH, McCammon K. Incontinence after Prostate Treatment: AUA/SUFU Guideline. J Urol. 2019 Aug;202(2):369-378. doi: 10.1097/JU.0000000000000314. Epub 2019 Jul 8.

  PMID: 31059663 BACKGROUND

• Huang X, Chen XX, Chen X, Chen QZ, Wang L, Li C, Tian JL. Feasibility of anterior lobe-preserving transurethral enucleation and resection of prostate on improving urinary incontinence in patients with benign prostatic hyperplasia: A retrospective cohort study. Medicine (Baltimore). 2023 Feb 17;102(7):e32884. doi: 10.1097/MD.0000000000032884.

  PMID: 36800610 BACKGROUND

• Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S. A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update. Eur Urol. 2015 Jun;67(6):1066-1096. doi: 10.1016/j.eururo.2014.06.017. Epub 2014 Jun 25.

  PMID: 24972732 BACKGROUND

• Magistro G, Schott M, Keller P, Tamalunas A, Atzler M, Stief CG, Westhofen T. Enucleation vs. Resection: A Matched-pair Analysis of TURP, HoLEP and Bipolar TUEP in Medium-sized Prostates. Urology. 2021 Aug;154:221-226. doi: 10.1016/j.urology.2021.04.004. Epub 2021 Apr 21.

  PMID: 33891930 BACKGROUND

• Pagano E, Laudato M, Griffo M, Capasso R. Phytotherapy of benign prostatic hyperplasia. A minireview. Phytother Res. 2014 Jul;28(7):949-55. doi: 10.1002/ptr.5084.

  PMID: 25165780 BACKGROUND

MeSH Terms

Conditions

Urinary Incontinence; Urinary Incontinence, Stress; Urinary Incontinence, Urge; Prostatic Hyperplasia

Condition Hierarchy (Ancestors)

Urination Disorders; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Lower Urinary Tract Symptoms; Urological Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Prostatic Diseases; Genital Diseases, Male; Genital Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Urology

Study Record Dates

• First Submitted: April 15, 2025
• First Posted: April 22, 2025
• Study Start: July 1, 2022
• Primary Completion: June 1, 2025
• Study Completion: July 1, 2025
• Last Updated: July 24, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)