NCT06934291

Brief Summary

The treatment of periodontitis requires the removal of dental biofilm through both professional mechanical plaque removal and at-home oral hygiene practices. This study aims to compare clinical and psychological outcomes following professional treatment using either piezoelectric or magnetostrictive ultrasonic devices.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 31, 2025

Completed
Same day until next milestone

Study Start

First participant enrolled

March 31, 2025

Completed
18 days until next milestone

First Posted

Study publicly available on registry

April 18, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2025

Completed
Last Updated

September 10, 2025

Status Verified

September 1, 2025

Enrollment Period

6 months

First QC Date

March 31, 2025

Last Update Submit

September 3, 2025

Conditions

Keywords

periodontitispatient centred outcomesmagnetostrictive

Outcome Measures

Primary Outcomes (3)

  • Pain perception

    vas scale (0-10) for perception of pain after treatment

    through study completition, on average 6 months

  • noise

    vas scale (0-10) for perception of noise after treatment

    through study completition, on average 6 months

  • vibration

    vas scale (0-10) for perception of vibration after treatment

    through study completition, on average 6 months

Secondary Outcomes (1)

  • pocket closure

    through study completition, on average 6 months

Study Arms (2)

Piezoelectric

ACTIVE COMPARATOR

Full-mouth ultrasonic debridement will be performed with a ultrasonic tip (vibration frequence \>18 kHz) powered by a piezoelectric device

Device: Full-mouth ultrasonic debridement with piezoelectric device (EMS, mini piezon)

Magnetostrictive

EXPERIMENTAL

Full-mouth ultrasonic debridement will be performed with a ultrasonic tip (vibration frequence \>18 kHz) powered by a magnetostrictive device.

Device: Full-mouth ultrasonic debridement with magnetostrictive device (Cavitron Select, Dentsply)

Interventions

the use of ultrasonic oscillating tips allows supragingival and subgingival biofilm and dental calculus removal

Piezoelectric

the use of ultrasonic oscillating tips allows supragingival and subgingival biofilm and dental calculus removal

Magnetostrictive

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \>18 years
  • periodontitis of stage 1 and 2
  • absence of systemic chronic disease

You may not qualify if:

  • anticoagulants treatment
  • antibiotic treatment 3 months before the screening visit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AOUS

Siena, SI, 53100, Italy

RECRUITING

MeSH Terms

Conditions

Chronic PeriodontitisPeriodontitis

Interventions

Emergency Treatment

Condition Hierarchy (Ancestors)

Periodontal DiseasesMouth DiseasesStomatognathic DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Therapeutics

Central Study Contacts

Nicola Discepoli, DDS, MSc

CONTACT

Nicola Discepoli, DDS, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 31, 2025

First Posted

April 18, 2025

Study Start

March 31, 2025

Primary Completion

October 1, 2025

Study Completion

October 1, 2025

Last Updated

September 10, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations