The Beijing Childhood Eye Study

NCT06931444 | Enrolling By Invitation

• 2 other identifiers: Beijing Childhood Eye StudyZ201100005520045
• Study Type: observational
• Target: 3,760
• Locations: 1 country
• Sites: 1

Brief Summary

Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma, and other complications. In the current study, we aim to observe the natural course of the development , progression, and its associated factors in children

Conditions

Myopia

Keywords

myopia; child; axial length; refractive error

Outcome Measures

Primary Outcomes (1)

• Myopia development

  Myopia was classified as a Spherical equivalent (SE) of -0.5 D or lower, and was further categorized into mild (-3 D \< SE ≤ -0.5 D), moderate (-6 D \< SE ≤ -3 D), and severe (SE ≤ -6 D). Hyperopia was classified as a SE of +1.0 D or greater. Intermediate refractive states (-0.5 D \< SE \< +1 D) were considered emmetropic. Astigmatism was defined as an absolute cylinder power of 0.75 diopters (D). Anisometropia were defined by an interocular SE difference of at least 1.0 D.

  3 years

Study Arms (1)

grades 1-3 students

Currently enrolled students in grades 1-3 of the selected primary schools, in good health, with normal ocular appearance. All enrolled students have no ocular diseases, no strabismus, ocular trauma, or history of intraocular surgery, with unaided visual acuity of 20/20 or better. Parents consent to participate in the survey and sign informed consent form.

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Grades 1-3 primary school students.

Sponsors & Collaborators

• Beijing Tongren Hospital: lead

Study Sites (1)

Beijing Tongren hospital

Beijing, Beijing Municipality, 100083, China

Location

MeSH Terms

Conditions

Myopia; Refractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 15, 2025
• First Posted: April 17, 2025
• Study Start: January 1, 2020
• Primary Completion: August 1, 2025
• Study Completion: September 1, 2025
• Last Updated: April 17, 2025

Record last verified: 2025-04

Locations

CN (1)