NCT06931353

Brief Summary

This study aims to investigate the association between preoperative anticholinergic drugs burden and postoperative delirium in elderly Chinese patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,536

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2020

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2022

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

April 9, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 17, 2025

Completed
Last Updated

April 17, 2025

Status Verified

April 1, 2025

Enrollment Period

2 years

First QC Date

April 9, 2025

Last Update Submit

April 9, 2025

Conditions

Delirium - Postoperative

Outcome Measures

Primary Outcomes (1)

  • postoperative delirium

    7 days after surgery

Eligibility Criteria

Age65 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients over 65 years

You may qualify if:

  • patients over 65 years; Undergoing general anesthesia; Inpatients who had surgery between Aprill 1, 2020 and Aprill 1, 2022.

You may not qualify if:

  • ASA grade V; preoperative Mini-Mental State Examination (MMSE) score \<24;history of neurological disorders (such as cerebrovascular disease or dementia); emergency surgeries; operative duration ≤30 minutes, and cases with \>5% missing data.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

First Medical Center of Chinese PLA General Hospital

Beijing, China

Location

MeSH Terms

Conditions

Emergence Delirium

Condition Hierarchy (Ancestors)

DeliriumConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and SymptomsNeurocognitive DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
associate chief physician

Study Record Dates

First Submitted

April 9, 2025

First Posted

April 17, 2025

Study Start

April 1, 2020

Primary Completion

April 1, 2022

Study Completion

April 1, 2022

Last Updated

April 17, 2025

Record last verified: 2025-04

Locations

CN(1)