Improving Breast Health Knowledge Among Women Using a Gamified Metaverse-Based Platform

NCT06930898 | Completed

• 2 other identifiers: Mammo2025-RCT01UMREC_3967
• Study Type: interventional
• Target: 72
• Locations: 2 countries
• Sites: 2

Brief Summary

This randomized controlled trial aimed to evaluate the effectiveness of Mammoverse, a gamified metaverse-based educational platform, in improving breast health knowledge among women in China. Participants were randomly assigned to either a gamified or non-gamified version of the platform. Both groups received identical educational content, but only the gamified group experienced interactive game elements such as avatars, progress feedback, and rewards. Knowledge was assessed at baseline, immediately post-intervention, and at 4-week follow-up. The study found that the gamified platform significantly improved knowledge retention and participant engagement compared to the non-gamified version. This ClinicalTrials.gov registration reflects only the randomized controlled trial (RCT) portion of a broader mixed-methods study that was approved by the University of Malaya Research Ethics Committee (Ref: UM.TNC2/UMREC\_3967). The full study protocol includes three methodological approaches, and this registration pertains specifically to the RCT component involving the Mammoverse platform. Other study components are not included in this registration.

Conditions

Health Education; Breast Neoplasms

Keywords

Gamification; Health Education; Breast Cancer Awareness; Metaverse; Women's Health; Digital Health Literacy

Outcome Measures

Primary Outcomes (1)

• Change in Breast Health Knowledge Score from Baseline to 4 Weeks Post-Intervention

  Assessed using an 18-item adapted Breast Health Literacy Questionnaire. Scores range from 0 to 18, with higher scores indicating greater knowledge. Main comparison is between baseline and 4-week follow-up.

  Baseline and 4 weeks post-intervention

Secondary Outcomes (1)

• Change in Breast Health Knowledge Score from Baseline to Immediately Post-Intervention

  Baseline and immediately post-intervention

Other Outcomes (1)

• Knowledge Retention from Immediately Post-Intervention to 4 Weeks Post

  Immediately post-intervention and 4 weeks post-intervention

Study Arms (2)

Gamified Metaverse Education

EXPERIMENTAL

Participants in this group used the Mammoverse platform with gamified features, including story-based missions, interactive tasks, point-based rewards, achievement badges, and virtual incentives. The educational content was delivered through immersive scenarios to enhance engagement and motivation in learning about breast health.

Behavioral: Gamified Mammoverse Platform

Non-Gamified Metaverse Education

ACTIVE COMPARATOR

Participants in this group accessed the Mammoverse platform without any gamified features. The virtual environment delivered identical breast health educational content, but without tasks, points, rewards, badges, or narrative elements.

Behavioral: Standard Mammoverse Platform

Interventions

Gamified Mammoverse Platform BEHAVIORAL

A gamified, metaverse-based platform delivering breast health education through story-based tasks, interactive challenges, points, rewards, badges, and virtual incentives.

Gamified Metaverse Education

Standard Mammoverse Platform BEHAVIORAL

A non-gamified version of the Mammoverse platform that provides the same breast health educational content.

Non-Gamified Metaverse Education

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female participants aged 18 years and above
• Able to read and understand Chinese
• Access to a digital device and stable internet connection
• Willing to provide informed consent

You may not qualify if:

• Cognitive impairment or mental health condition that affects participation
• Inability to complete the full intervention and follow-up sessions
• Incomplete baseline assessment

Sponsors & Collaborators

• University of Malaya: lead

Study Sites (2)

Online Recruitment - Hangzhou, Zhejiang, China

Hangzhou, Zhejiang, 31000, China

Location

University of Malaya

Kuala Lumpur, Malaysia

Location

Related Publications (1)

• Li R, Kahn SM, Duan B, Wong SY. Gamified Versus Non-gamified Metaverse Learning for Breast Health Knowledge in Women: Randomized Controlled Trial. JMIR Serious Games. 2026 Jan 6. doi: 10.2196/75318. Online ahead of print.

  PMID: 41499212 DERIVED

MeSH Terms

Conditions

Health Education; Breast Neoplasms

Condition Hierarchy (Ancestors)

Adherence Interventions; Medication Adherence; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior; Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Rui Li, PhD(c)

  University of Malaya

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants were randomly assigned in a 1:1 ratio to one of two parallel groups: a gamified version of the Mammoverse metaverse-based platform or a non-gamified version containing the same educational content.

Study Record Dates

• First Submitted: April 8, 2025
• First Posted: April 16, 2025
• Study Start: December 1, 2024
• Primary Completion: February 1, 2025
• Study Completion: March 24, 2025
• Last Updated: April 18, 2025

Record last verified: 2025-04

Locations

MY (1); CN (1)