Risk Factors , Types and Neuroimaging Findings in Patients With Cerebral Palsy at Assiut University Children's Hospital

NCT06928012 | Not Yet Recruiting

• 1 other identifier: Cerebral palsy neuroimaging
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cerebral palsy (CP) is the most common motor disorder among children as its worldwide prevalence is ranging from 1.5 to more than 4 per 1000 live births or children of a defined age range.

• Pediatric cerebral palsy is a clinical syndrome caused by brain injury or lesions in children from before birth to 1 month after birth, and mainly manifests as non progressive central dyskinesia and abnormal posture.
• Research has shown that the prevalence of cerebral palsy in children worldwide is about 3.16% , and results in heavy familial and social burdens as well as usage of medical resources, Despite considerable research , the complex etiology and pathogenesis of cerebral palsy remain unclear. The high-risk factors of cerebral palsy are complex and diverse (CP) appeared to be more prevalent in low- or middle-income countries than in high-income countries. (CP) prevalence was about 3.6 and 2.9 per 1000 children in Uganda and Egypt, respectively, but the prevalence was 1.8 to 2.3 cases per 1000 children in the USA, Europe, and Australia.
• Cerebral palsy (CP) describes a group of disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. It begins in early childhood and persists through the lifespan. It was first reported as a movement disorder in the historical documents of the Sumerians, and Hippocrates.
• Cerebral palsy (CP) is the major cause of motor impairment in young children, The clinical picture changes over time, and a recent review showed that referral for diagnosis typically happens between 10 and 21 months of age.

Conditions

Cerebral Palsy

Outcome Measures

Primary Outcomes (3)

• Evaluation of risk factors of pediatric cerebral palsy

  to evaluate different risk factors of pediatric cerebral palsy

  Baseline

• Evaluation of types of pediatric cerebral palsy

  to evaluate different types of pediatric cerebral palsy

  Baseline

• Evaluation of neuroimaging of of pediatric cerebral palsy

  Evaluation of neuroimaging of of pediatric cerebral palsy

  Baseline

Eligibility Criteria

• Age: 6 Months - 16 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Cerebral patient admitted to Assiut university within one year

You may qualify if:

• cerebral palsy is defined as a group of permanent disorder of posture and movement resulting from a non-progressive disturbance which occurred in fetal or infant brain .
• Children ages 6 months to 16 years.

You may not qualify if:

• Children with identified chromosomal abnormalities or syndromatic features
• Progressive condition is identified to cause the movement, development, and posture disorder.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: March 22, 2025
• First Posted: April 15, 2025
• Study Start: May 1, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: April 15, 2025

Record last verified: 2025-03