Regional Analgesia at the Pediatric Emergency Department

NCT06927193 | Recruiting

• 1 other identifier: 0035-25-HYMC
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

Approximately two years ago, ultrasound-guided regional blocks technique was introduced into routine use in the pediatric emergency department at Hillel Yaffe Medical Center. Since then, nearly 300 different blocks have been performed. Study Objective: To collect a registry database of complication rates associated with regional analgesia during routine pediatric emergency department care between 2023 and 2025.

Conditions

Regional Anaesthesia

Outcome Measures

Primary Outcomes (1)

• Any complication

  Any complication that happend to the patient because of the regional anaesthesia.

  2 years

Study Arms (1)

Regional anaesthesia

Children who underwent regional analgesia during routine pediatric emergency department

Procedure: Regional anaesthesia

Interventions

Regional anaesthesia PROCEDURE

Regional anaesthesia

Regional anaesthesia

Eligibility Criteria

• Age: Up to 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children who visited the pediatric emergency department between 2023-2025

You may qualify if:

• Children who visited the pediatric emergency department between 2023-2025 and underwent a nerve block during their visit.

You may not qualify if:

• Children who visited the emergency department but had the nerve block performed outside the emargency department setting (e.g., inpatient wards or operationg room), or if the block was performed by a physician not affiliated with the pediatric emergency department.

Sponsors & Collaborators

• Hillel Yaffe Medical Center: lead

Study Sites (1)

Hillel Yaffe medical center

Hadera, 38100, Israel

RECRUITING

Related Publications (8)

• Katzir Y, Ganor L, Berant R, Shahar-Nissan K. Building Blocks-A Block-by-Block Approach to Better Emergency Care in Children. Pediatr Emerg Care. 2024 Jun 1;40(6):463-468. doi: 10.1097/PEC.0000000000003201. Epub 2024 Apr 2.

  PMID: 38563828 BACKGROUND

• Shahar-Nissan K, Berant R, Ganor L, Katzir Y. Ultrasound-Guided Supraclavicular Brachial Plexus Blocks Performed by Pediatric Emergency Medicine Physicians for Painful Orthopedic Procedures in a Pediatric Emergency Department-A Case Series. Pediatr Emerg Care. 2022 Dec 1;38(12):e1684-e1687. doi: 10.1097/PEC.0000000000002878. Epub 2022 Nov 18.

  PMID: 36449743 BACKGROUND

• Ruest S, Anderson A. Management of acute pediatric pain in the emergency department. Curr Opin Pediatr. 2016 Jun;28(3):298-304. doi: 10.1097/MOP.0000000000000347.

  PMID: 26974975 BACKGROUND

• Walker BJ, Long JB, Sathyamoorthy M, Birstler J, Wolf C, Bosenberg AT, Flack SH, Krane EJ, Sethna NF, Suresh S, Taenzer AH, Polaner DM, Martin L, Anderson C, Sunder R, Adams T, Martin L, Pankovich M, Sawardekar A, Birmingham P, Marcelino R, Ramarmurthi RJ, Szmuk P, Ungar GK, Lozano S, Boretsky K, Jain R, Matuszczak M, Petersen TR, Dillow J, Power R, Nguyen K, Lee BH, Chan L, Pineda J, Hutchins J, Mendoza K, Spisak K, Shah A, DelPizzo K, Dong N, Yalamanchili V, Venable C, Williams CA, Chaudahari R, Ohkawa S, Usljebrka H, Bhalla T, Vanzillotta PP, Apiliogullari S, Franklin AD, Ando A, Pestieau SR, Wright C, Rosenbloom J, Anderson T; Pediatric Regional Anesthesia Network Investigators. Complications in Pediatric Regional Anesthesia: An Analysis of More than 100,000 Blocks from the Pediatric Regional Anesthesia Network. Anesthesiology. 2018 Oct;129(4):721-732. doi: 10.1097/ALN.0000000000002372.

  PMID: 30074928 BACKGROUND

• Frenkel O, Liebmann O, Fischer JW. Ultrasound-guided forearm nerve blocks in kids: a novel method for pain control in the treatment of hand-injured pediatric patients in the emergency department. Pediatr Emerg Care. 2015 Apr;31(4):255-9. doi: 10.1097/PEC.0000000000000398.

  PMID: 25803747 BACKGROUND

• Baker MD, Gullett JP. Ultrasound-Guided Femoral Nerve Blocks. Pediatr Emerg Care. 2015 Dec;31(12):864-8; quiz 869-71. doi: 10.1097/PEC.0000000000000634.

  PMID: 26626896 BACKGROUND

• Heffler MA, Brant JA, Singh A, Toney AG, Harel-Sterling M, Grandjean-Blanchet C, Riera A, Khalil PA, Starr-Seal RL, Binder ZW. Ultrasound-Guided Regional Anesthesia of the Femoral Nerve in the Pediatric Emergency Department. Pediatr Emerg Care. 2023 Feb 1;39(2):e30-e34. doi: 10.1097/PEC.0000000000002607. Epub 2022 Jan 12.

  PMID: 35245015 BACKGROUND

• Argiris A, Heald P, Kuzel T, Foss FM, DiStasio S, Cooper DL, Arbuck S, Murren JR. Phase II trial of 9-aminocamptothecin as a 72-h infusion in cutaneous T-cell lymphoma. Invest New Drugs. 2001;19(4):321-6. doi: 10.1023/a:1010613912335.

  PMID: 11561692 BACKGROUND

MeSH Terms

Interventions

Anesthesia, Conduction

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia

Study Officials

• Erez Nadir, MD

  Hillel Yaffe Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Erez Nadir, MD

CONTACT

+9724774379; erezn@hymc.gov.il

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Neonatologist

Study Record Dates

• First Submitted: April 6, 2025
• First Posted: April 15, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): January 1, 2027
• Last Updated: April 9, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

IL (1)