Tricuspid RegurgitAtion rIsk modeL Study (TRAIL Study)
1 other identifier
observational
3,000
1 country
7
Brief Summary
This study is a multicenter cohort study including patients diagnosed with tricuspid regurgitation during hospitalization. The primary outcome of the study is all-cause death, and the secondary outcome is cardiovascular events. The prognostic risk factors of patients with tricuspid regurgitation are evaluated, and the prognostic models are constructed through the follow-up observation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2016
Longer than P75 for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 15, 2016
CompletedFirst Submitted
Initial submission to the registry
March 24, 2025
CompletedFirst Posted
Study publicly available on registry
April 15, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 15, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 15, 2030
April 15, 2025
April 1, 2025
14 years
March 24, 2025
April 11, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
all-cause mortality
Death due to any cause after enrollment
Through study completion, an average of 5 years
Secondary Outcomes (2)
Cardiovascular death
Through study completion, an average of 5 years
Heart Failure Hospitalization
Through study completion, an average of 5 years
Eligibility Criteria
Adult patients diagnosed with tricuspid regurgitation (TR) during hospitalization were enrolled.
You may qualify if:
- Aged over 18 yrs.
- Patients diagnosed with tricuspid regurgitation during hospitalization.
You may not qualify if:
- Patients unable to provide informed consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sun Yat-sen Universitylead
- First Affiliated Hospital, Sun Yat-Sen Universitycollaborator
- Third Affiliated Hospital, Sun Yat-Sen Universitycollaborator
- Affiliated Hospital of Guangdong Medical Universitycollaborator
- Second Affiliated Hospital of Shantou University Medical Collegecollaborator
- Eighth Affiliated Hospital, Sun Yat-sen Universitycollaborator
- Zhongshan People's Hospital, Guangdong, Chinacollaborator
- Jieyang People's Hospitalcollaborator
Study Sites (7)
The First Affiliated Hospital of Sun Yat-sen Univerity
Guangzhou, Guangdong, 510000, China
Third Affiliated Hospital, Sun Yat-Sun University,
Guangzhou, Guangdong, 510000, China
Jieyang People's Hospital
Jieyang, Guangdong, 522000, China
Second Affiliated Hospital of Shantou University Medical College
Shantou, Guangdong, 515041, China
Eighth Affiliated Hospital, Sun Yat-Sen University
Shenzhen, Guangdong, 518000, China
Affiliated Hospital of Guangdong Medical University
Zhanjiang, Guangdong, 524001, China
Zhongshan People's Hospital
Zhongshan, Guangdong, 528400, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 15 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
March 24, 2025
First Posted
April 15, 2025
Study Start
June 15, 2016
Primary Completion (Estimated)
June 15, 2030
Study Completion (Estimated)
June 15, 2030
Last Updated
April 15, 2025
Record last verified: 2025-04