Key Insights

Highlights

Success Rate

93% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

1.8%

2 terminated out of 111 trials

Success Rate

93.3%

+6.8% vs benchmark

Late-Stage Pipeline

5%

5 trials in Phase 3/4

Results Transparency

18%

5 of 28 completed with results

Key Signals

5 with results93% success

Data Visualizations

Phase Distribution

64Total
Not Applicable (58)
P 1 (1)
P 3 (3)
P 4 (2)

Trial Status

Recruiting36
Completed28
Unknown13
Active Not Recruiting13
Not Yet Recruiting11
Enrolling By Invitation5

Trial Success Rate

93.3%

Benchmark: 86.6%

Based on 28 completed trials

Clinical Trials (111)

Showing 20 of 20 trials
NCT04433065Not ApplicableActive Not RecruitingPrimary

TTVR Early Feasibility Study

NCT06183684Not ApplicableRecruitingPrimary

Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

NCT07171060Not ApplicableRecruitingPrimary

Laplace Early Feasibility Study - Canada

NCT03745313Not ApplicableCompletedPrimary

Edwards CLASP TR EFS

NCT04097145Not ApplicableRecruitingPrimary

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

NCT05556460Not ApplicableRecruitingPrimary

Safety and Effectiveness Study of DragonFly-T System for Severe Tricuspid Regurgitation

NCT07534917Not Yet Recruiting

Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.

NCT07623083Not Yet Recruiting

Evaluation of a Management Algorithm for TAVI Patients With Concomitant Mitral or Tricuspid Regurgitation

NCT05913908Not ApplicableRecruitingPrimary

EFS of the DUO System for Tricuspid Regurgitation

NCT07605624Not Yet Recruiting

Active Post-Market Surveillance of Innovative Devices for Valvular Heart Disease

NCT04761120Recruiting

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

NCT04100720Not ApplicableWithdrawnPrimary

Early Feasibility Study of the Cardiovalve System for Tricuspid Regurgitation

NCT05486832Not ApplicableActive Not RecruitingPrimary

TARGET Study: Safety and Performance of the Cardiovalve TR Replacement System

NCT07334691Not ApplicableRecruitingPrimary

TARGET 2.0 Study: Safety and Performance of the Cardiovalve TR Replacement System

NCT05825898Enrolling By InvitationPrimary

Outcome of Patients With Severe Functional TR According to Medical, Transcatheter or Surgical Treatment

NCT05064514Not ApplicableActive Not RecruitingPrimary

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease

NCT03382457Not ApplicableActive Not RecruitingPrimary

Clinical Study of Edwards Cardioband FIT Valve Repair System

NCT04093297Not ApplicableEnrolling By InvitationPrimary

Band Versus Ring for Tricuspid Regurgitation

NCT05848284Not ApplicableRecruitingPrimary

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

NCT04570163RecruitingPrimary

Berlin Registry of Right Heart Interventions

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