NCT06926296

Brief Summary

Healthcare professionals are facing an escalating crisis, with burnout rates ranging between 40% and 60% and a growing intention to leave the profession, affecting one in five physicians and one in four nurses in the coming years. While current interventions focused on individual resilience, such as mindfulness, peer support, and workload management, have been promoted as solutions, they have failed to bring about systemic improvements. This raises the question of whether other factors, such as Moral Injury, play a key role in this crisis. Moral Injury is an emerging concept that highlights the profound misalignment between healthcare workers' professional values and the reality of their practice, often exacerbated by organizational and economic constraints. The objective of this study is to describe the manifestations of Moral Injury among healthcare professionals in France. By establishing the first large-scale assessment of Moral Injury among healthcare professionals in France, this study aims to identify key organizational and personal risk factors contributing to this phenomenon. The use of Structural Equation Modeling will help build a robust theoretical model that clarifies the underlying mechanisms of Moral Injury and its interactions with broader health issues. The findings will support the development of targeted interventions focused on systemic organizational changes to improve healthcare workers' well-being and guide public health policies.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,073

participants targeted

Target at P75+ for not_applicable

Timeline
6mo left

Started Nov 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress49%
Nov 2025Nov 2026

First Submitted

Initial submission to the registry

April 7, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 13, 2025

Completed
7 months until next milestone

Study Start

First participant enrolled

November 19, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Expected
Last Updated

April 14, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

April 7, 2025

Last Update Submit

April 13, 2026

Conditions

Moral Injury

Keywords

Moral injuryBurnoutDepressionAnxietyHealthcare workersHealth services research

Outcome Measures

Primary Outcomes (1)

  • Moral Injury Inventory for Healthcare Professionals

    An overall score out of 100 will be created for the inventory, where a high score indicates a high level of "Moral Injury"

    One point : baseline

Secondary Outcomes (3)

  • Moral Injury Events Scale

    One point : baseline

  • Maslach Burnout Inventory

    One point : baseline

  • EuroQol 5-Dimensions (EQ-5D)

    One point : baseline

Study Arms (1)

Healthcare workers

OTHER

All health professionals working in metropolitan France and the French overseas departments and territories

Other: Self-Questionnaires for Healthcare Workers

Interventions

Self-Questionnaires for Healthcare WorkersOTHER

Health workers will be invited to complete an online self-questionnaire.

Healthcare workers

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthcare workers

You may not qualify if:

  • Absence of consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier Intercommunal Toulon-La Seyne sur Mer

Toulon, Var, 83100, France

RECRUITING

Related Publications (2)

  • Boyer L, Fond G, Tran B, Llorca PM, Duclos A. The hidden crisis: Moral injury among French healthcare workers. J Epidemiol Popul Health. 2024 Dec;72(6):202780. doi: 10.1016/j.jeph.2024.202780. Epub 2024 Oct 19.

    PMID: 39427511BACKGROUND

  • Dean W, Morris D, Llorca PM, Talbot SG, Fond G, Duclos A, Boyer L. Moral Injury and the Global Health Workforce Crisis - Insights from an International Partnership. N Engl J Med. 2024 Sep 5;391(9):782-785. doi: 10.1056/NEJMp2402833. Epub 2024 Aug 31. No abstract available.

    PMID: 39216090BACKGROUND

MeSH Terms

Conditions

Stress Disorders, Post-TraumaticBurnout, PsychologicalDepressionAnxiety Disorders

Interventions

Health Personnel

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental DisordersStress, PsychologicalBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Health Care Facilities Workforce and Services

Study Officials

  • Laurent BOYER, Pr

    CEReSS

    STUDY DIRECTOR

Central Study Contacts

Sophie LAFOND

CONTACT

0483772062sophie.lafond@ch-toulon.fr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 7, 2025

First Posted

April 13, 2025

Study Start

November 19, 2025

Primary Completion

May 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

April 14, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)