Accuracy of Transcranial Colour Coded Duplex in Comparing With CT Angiography

NCT06920303 | Recruiting FDA Device

• 1 other identifier: Soh-Med--25-3-01MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Investigator will compare accuracy of transcranial colour coded duplex with CT angiography in detecting arterial obstructions in patients presenting or with history of cerebrovascular ischemic strokes

Conditions

Ischemic Stroke, Acute

Keywords

transcranial colour coded duplex; ct angiography

Outcome Measures

Primary Outcomes (1)

• detect accuracy of transcranial color coded duplex compared with CT angiography in diagnosing arterial obstructions in acute ischemic stroke

  investigator will detect if transcranial color coded duplex can be used for diagnosing arterial obstructions in acute ischemic stroke by measuring the peak systolic velocity of different intracranial arteries, investigator will compare with CT angiography imaging results to assess the accuracy of transcranial color coded duplex in diagnosis of acute ischemic stroke.

  one year after enrolling one hundred cases

Study Arms (1)

patients who suffer from ischemic cerebrovascular stroke

All subjects must meet the following criteria to be enrolled in the study, patients who have ischemic strokes or transient ischemic attacks and will be admitted in department of neurology and psychological medicine and stroke unit at Sohag university hospital.

Device: transcranial colour coded duplex

Interventions

transcranial colour coded duplex DEVICE

transcranial colour coded duplex is good non invasive tool in detect velocity and obstructions of intracranial arteries

patients who suffer from ischemic cerebrovascular stroke

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

one hundred cases of patients with acute ischemiac cerebrovascular stroke will be included in the study

You may qualify if:

• patients who have acute ischemic strokes or transient ischemic attacks .

You may not qualify if:

• Patients with history of cardiac arrhythmia or discovered recently or known rheumatic heart disease.
• Patients with history of autoimmune diseases.
• Patients with space occupying lesion or hemorrhage in Ct brain.
• Pregnant female.
• Patients who refuse to participate in the study.
• Patients who have history of allergy or developed acute kidney injury during previous dye injection.
• Patients who have chronic kidney disease.
• Premorbid neurological disorder (myopathy, multiple sclerosis) on neurological examination or previous investigations.
• Inability to achieve safe vascular access.
• Patients with insufficient temporal acoustic window.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university hospital

Sohag, Egypt

RECRUITING

Related Publications (1)

• 1. DALYs GBD, Collaborators H. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1859-922. 2. Johansson BB. Hypertension mechanisms causing stroke. Clin Exp Pharmacol Physiol. 1999;26(7):563-5.. 3. Grau AJ, Weimar C, Buggle F, Heinrich A, Goertler M, Neumaier S, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke. 2001;32(11):2559-66.. 4. Meseguer E, Lavallee PC, Mazighi M, et al. Yield of systematic transcranial Doppler in patients with transient ischemic attack. Ann Neurol 2010;68:9-17.

  BACKGROUND

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Hassan H Accuracy of Transcranial Colour Coded duplex Compared With CT, resident

CONTACT

+2001060583440; hassan.hamdy@med.sohag.edu.eg

Hazem K Ebrahim, professor

CONTACT

+2001020044243

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 3 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident-neurology and psychological medicine department-Sohag hospital university

Study Record Dates

• First Submitted: March 30, 2025
• First Posted: April 9, 2025
• Study Start: May 1, 2025
• Primary Completion: January 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: May 13, 2025

Record last verified: 2025-04

Locations

EG (1)