Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies

NCT06913205 | Completed

• 1 other identifier: 2011-KAEK-25 2021/08-20
• Study Type: observational
• Target: 145
• Locations: 1 country
• Sites: 1

Brief Summary

Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain. Regional nerve block techniques are recommended for postoperative pain management. This research compared the two most frequently used methods: rectus sheath block and local wound infiltration.

Conditions

Appendectomy, Laparoscopic; Pediatric Anesthesia; Nerve Block/Methods; Regional Anesthesia; Acute Pain, Postoperative

Keywords

laparoscopic appendectomy; pediatric anesthesia; nerve blocks; regional anesthesia; acute postoperative pain

Outcome Measures

Primary Outcomes (1)

• Analgesic consumption

  Total acetaminophen use in the first 24 hours after surgery

  Postoperative first 24 hours.

Secondary Outcomes (1)

• Postoperative pain scores

  Postoperative first 24 hours.

Study Arms (2)

Rectus Sheath Block

Children undergoing laparoscopic appendectomy with rectus sheath blocks

Local infiltration

Children undergoing laparoscopic appendectomy with local infiltration

Eligibility Criteria

• Age: 8 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children undergoing laparoscopic appendectomy surgery in Bursa Yuksek Ihtisas Training and Research Hospital

You may qualify if:

• Older than 8 years
• Younger than 18 years
• Minimal invasive appendectomy (3 port)
• Consent to participate

You may not qualify if:

• Younger than 8 years
• Older than 18 years
• Convert to open abdominal surgery
• Do not consent to participate

Sponsors & Collaborators

• Bursa City Hospital: lead

Study Sites (1)

University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital

Bursa, Bursa, 16110, Turkey (Türkiye)

Location

Related Publications (4)

• Hamill JK, Liley A, Hill AG. Rectus sheath block for laparoscopic appendicectomy: a randomized clinical trial. ANZ J Surg. 2015 Dec;85(12):951-6. doi: 10.1111/ans.12950. Epub 2015 Jan 12.

  PMID: 25581711 BACKGROUND

• Liu Y, Seipel C, Lopez ME, Nuchtern JG, Brandt ML, Fallon SC, Manyang PA, Tjia IM, Baijal RG, Watcha MF. A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children. Paediatr Anaesth. 2013 Dec;23(12):1187-92. doi: 10.1111/pan.12271. Epub 2013 Sep 25.

  PMID: 24112856 BACKGROUND

• Tomecka MJ, Bortsov AV, Miller NR, Solano N, Narron J, McNaull PP, Ricketts KJ, Lupa CM, McLean SA. Substantial postoperative pain is common among children undergoing laparoscopic appendectomy. Paediatr Anaesth. 2012 Feb;22(2):130-5. doi: 10.1111/j.1460-9592.2011.03711.x. Epub 2011 Sep 29.

  PMID: 21958060 BACKGROUND

• Gurbuz H, Karasu D, Dogan AK, Kilicarslan N. Rectus sheath blocks for pediatric laparoscopic appendicectomy. BMC Anesthesiol. 2025 Sep 29;25(1):462. doi: 10.1186/s12871-025-03364-9.

  PMID: 41023777 DERIVED

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof. MD. PhD

Study Record Dates

• First Submitted: March 29, 2025
• First Posted: April 6, 2025
• Study Start: August 25, 2021
• Primary Completion: August 25, 2022
• Study Completion: March 25, 2025
• Last Updated: April 6, 2025

Record last verified: 2025-03

Locations

TU (1)