Tianjin Diabetes and Health Cohort Study

NCT06913153 | Completed Results

• 1 other identifier: TMUhMEC20250002
• Study Type: observational
• Target: 396,983
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this observational study is to reveal the natural history of diabetes and the occurrence and development patterns of its complications, to evaluate the effectiveness of diabetes interventions, and to assess the health and medical burdens caused by diabetes in Tianjin, based on the medical records and health big data in Tianjin and correspondingly constructed diabetes-specific cohort.

Conditions

Diabetes Mellitus

Keywords

cohort study; diabets complication; etiology; clinical epidemiology; health economic evaluation

Outcome Measures

Primary Outcomes (1)

• Diabetes Complications

  Diabetic Complications: diabetic retinopathy,diabetic nephropathy,cerebral infarction,coronary artery disease The diagnosis of coronary artery disease is based on a comprehensive assessment of the degree of coronary artery stenosis and evidence of myocardial ischemia, taking into account risk factors and clinical symptoms, and exclusion of other similar diseases. The diagnostic criteria for diabetic nephropathy are history of diabetes: clear and long history of diabetes, Urine protein test:Urinary microalbumin excretion rate (UACR) is a key indicator for early diagnosis, with a normal value of less than 30mg/g, 30-300m Diagnosis of diabetic retinopathy by fundus examination. Diagnostic criteria for cerebral infarction are ICD codes or the doctor's diagnosis. Data collection through chart review, patient self-reporting, imaging

  Baseline and week 520

Secondary Outcomes (2)

• Glycemic Control

  baseline and week 520

• Death

  baseline and week 520

Interventions

Diet BEHAVIORAL

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study was conducted through the University-Enterprise Joint Laboratory for Diabetes Epidemiology Research at Tianjin Medical University, China. Longitudinal multi-source health big data from 2009 to 2024 (encompassing 396,983 individuals with diabetes treated in secondary and tertiary healthcare facilities in Tianjin) were integrated to establish a representative diabetes population cohort.

You may qualify if:

• Patients diagnosed with diabetes
• Patients with three or more recorded visits
• The following information was complete at the first visit: age, sex, Blood Glucoseor ,glycated hemoglobin(HbA1c)

You may not qualify if:

• none

Sponsors & Collaborators

• Tianjin Medical University: lead

MeSH Terms

Conditions

Diabetes Mellitus

Interventions

Diet

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Nutritional Physiological Phenomena; Diet, Food, and Nutrition; Physiological Phenomena

Results Point of Contact

• Title: Zhenqiang Song, M.S., Associate Professor and Master's Supervisor
• Organization: Tianjin Medical University

Zsong@tmu.edu.cn

8622-18602276218

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Researcher，Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University

Study Record Dates

• First Submitted: March 29, 2025
• First Posted: April 6, 2025
• Study Start: January 1, 2009
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: May 25, 2025
• Results First Posted: May 25, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share