Cohort of Mexican Children With Diabetes Mellitus (CMC-DM)
CMC-DM
Characteristics and Evolution of Diabetes Mellitus in Mexican Children: Cohort Study
1 other identifier
observational
500
1 country
1
Brief Summary
The aim of this study is the identification of complications in diabetes mellitus pediatric patients and to compare the clinical, anthropometric, and biochemical characteristics between children in the different types of diabetes mellitus.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2008
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2008
CompletedFirst Submitted
Initial submission to the registry
March 18, 2016
CompletedFirst Posted
Study publicly available on registry
March 30, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2030
ExpectedAugust 22, 2017
August 1, 2017
12.8 years
March 18, 2016
August 17, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (7)
Diabetic retinopathy
A microvascular complication determined by ophthalmological evaluation
year 3
Peripheral diabetic neuropathy
A microvascular complication determined by neurological exam in either foot
year 5
Nerve damage
A microvascular complication determined by nerve conduction study in either foot
year 5
Microalbuminuria
A microvascular complication determined by urine albumin excretion \>= 30 mg/day
annual
Cardiac function
A cardiovascular risk indicator determined by echocardiogram
year 5
Cognitive evaluation
Determined by scores on the Mini-Mental State Examination
year 3
Intelligence quotient evaluation
Determined by Intelligence quotient test
year 3
Secondary Outcomes (9)
Body composition
annual
Glycemic control
annual
Beta cell function
annual
Pancreatic autoimmunity
onset of diabetes
Insulin resistance
annual
- +4 more secondary outcomes
Study Arms (4)
Type 1 diabetes mellitus
Sudden onset of symptoms and non-overweight/obese
Type 2 diabetes mellitus
Insidious onset of symptoms and overweight/obese
Type 1.5 diabetes mellitus
Overlap of type 1 and type2 diabetes mellitus clinical characteristics
Other types of diabetes mellitus
According American Diabetes Association criteria
Eligibility Criteria
Children and adolescents (boys and girls) from 1 months to 17 years of age that had recently been diagnosed with diabetes mellitus.
You may qualify if:
- Patients with confirmed diagnosis of diabetes mellitus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hospital Regional de Alta Especialidad del Bajío
León, Guanajuato, 37660, Mexico
Related Publications (1)
Evia-Viscarra ML, Guardado-Mendoza R, Rodea-Montero ER. Clinical and Metabolic Characteristics among Mexican Children with Different Types of Diabetes Mellitus. PLoS One. 2016 Dec 16;11(12):e0168377. doi: 10.1371/journal.pone.0168377. eCollection 2016.
PMID: 27992493DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
María L Evia-Viscarra
Department of Pediatric Endocrinology, Hospital Regional de Alta Especialidad del Bajío
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Pediatric Endocrinologist
Study Record Dates
First Submitted
March 18, 2016
First Posted
March 30, 2016
Study Start
March 1, 2008
Primary Completion
December 1, 2020
Study Completion (Estimated)
December 1, 2030
Last Updated
August 22, 2017
Record last verified: 2017-08