Efficacy of Matcha Tea on Patients With Biofilm-induced Gingivitis

NCT06912958 | Completed DMC

• 1 other identifier: Matcha tea on gingivitis
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.Evaluate the salivary level of antioxidants (malondialdehyde "MDA," superoxide dismutase "SOD," and glutathione peroxidase-1 "GPX-1") by enzyme-linked immunosorbent assay test (ELISA).
2. 2.Measuring clinical periodontal parameters, which are plaque index (PI), bleeding on probing (BOP), and gingival index (GI), between the baseline and endpoint of the study, which is one month.

Conditions

Gingivitis

Outcome Measures

Primary Outcomes (1)

• Evaluate the antioxidant effects of Matcha tea in daily intake for gingivitis patients.

  Evaluate the salivary level of antioxidants (malondialdehyde "MDA," superoxide dismutase "SOD," and glutathione peroxidase-1 "GPX-1") by enzyme-linked immunosorbent assay test (ELISA).

  One month

Secondary Outcomes (1)

• Measuring the changes in the clinical periodontal parameters

  one month

Study Arms (2)

Matcha tea group

EXPERIMENTAL

Intake of two cups daily for a month of matcha tea with oral hygiene instructions.

Dietary Supplement: Drinking of matcha tea; Dietary Supplement: Organic Japanese Matcha, Jade Leaf, Japan

Control group

NO INTERVENTION

Oral hygiene instructions, which include brushing teeth and flossing twice daily.

Interventions

Drinking of matcha tea DIETARY_SUPPLEMENT

Japanese tea that will take twice daily for one month

Matcha tea group

Organic Japanese Matcha, Jade Leaf, Japan DIETARY_SUPPLEMENT

dietary intake

Also known as: Lot T47I10P100

Matcha tea group

Eligibility Criteria

• Age: 16 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Having at least 20 teeth.
• gingivitis patient ( BOP\<10% , PPD = or \<3mm , no CAL , Have plaque index =1 ( according to Quigley-hein plaque index )
• No history of systemic disease.
• No medical treatment that impact periodontal status at last 6 months before examination and sampling.
• life style control

You may not qualify if:

• \*pregnant or in the period of breast feeding.
• smokers and alcoholics.
• Patients wearing orthodontic appliances.
• has history of systemic disease.
• periodontitis patient

Sponsors & Collaborators

• Ahmed Talib: lead

Study Sites (1)

Baghdad university

Baghdad, City of Medicine, Alrafedain street, Iraq

Location

Related Publications (3)

• (Carr A.C et al ,2017)

  BACKGROUND

• (Jakubczyk K et al ,2020)

  BACKGROUND

• (Lobo et al, 2010

  BACKGROUND

MeSH Terms

Conditions

Gingivitis

Condition Hierarchy (Ancestors)

Infections; Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Clinical researcher

Model Details: The first group recieve the drug A. While the second group will recieve drug B

Study Record Dates

• First Submitted: March 27, 2025
• First Posted: April 6, 2025
• Study Start: November 17, 2024
• Primary Completion: January 27, 2025
• Study Completion: February 4, 2025
• Last Updated: April 6, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)