NCT06911723

Brief Summary

This is a study investigating how brief online activities can influence mood and attitudes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
31mo left

Started Aug 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress22%
Aug 2025Dec 2028

First Submitted

Initial submission to the registry

March 18, 2025

Completed
17 days until next milestone

First Posted

Study publicly available on registry

April 4, 2025

Completed
5 months until next milestone

Study Start

First participant enrolled

August 20, 2025

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2028

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

August 29, 2025

Status Verified

August 1, 2025

Enrollment Period

3.1 years

First QC Date

March 18, 2025

Last Update Submit

August 22, 2025

Conditions

Schizophrenia Disorders

Outcome Measures

Primary Outcomes (3)

  • Patient Health Questionnaire - PHQ-9

    Depression measure

    Assessed at baseline (day 1) and after study completion, an average of a week

  • Generalized Anxiety Disorder 7-item - GAD-7

    Anxiety measure

    Assessed at baseline (day 1) and after study completion, an average of a week

  • The Motivation and Pleasure Scale-Self-Report - MAP-SR

    Negative symptoms

    Assessed at baseline (day 1) and after study completion, an average of a week

Study Arms (2)

Emotion Coping Activities

EXPERIMENTAL
Behavioral: Brief Activities

Belief Modifying Activities

EXPERIMENTAL
Behavioral: Brief Activities

Interventions

Brief ActivitiesBEHAVIORAL

The activities will be completed online.

Belief Modifying ActivitiesEmotion Coping Activities

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • aged 18-65
  • schizophrenia group - have a psychotic disorder diagnosis
  • healthy control group - Do not have a current DSM-5 diagnosis via the SCID-5

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35223-1517, United States

RECRUITING

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic DisordersMental Disorders

Central Study Contacts

Lauren Luther, PhD

CONTACT

(205) 934-3850cas-treatlab@uab.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 18, 2025

First Posted

April 4, 2025

Study Start

August 20, 2025

Primary Completion (Estimated)

October 1, 2028

Study Completion (Estimated)

December 1, 2028

Last Updated

August 29, 2025

Record last verified: 2025-08

Locations

US(1)