Dementia Prevention Internet-Based Intervention: Randomized Controlled Trial and Knowledge Translation

NCT06911047 | Withdrawn

• 1 other identifier: Levinson_DCI
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

In this proposal, the investigators plan to study the effectiveness of a web-based intervention on dementia prevention knowledge, intentions, and behaviour change related to dementia risk. Participants will be randomized to one of two groups - intervention and control. Participants randomized to the intervention group will receive the dementia prevention e-learning. Participants in the control group will be assigned an alternate-topic e-learning lesson. All participants will be given access to all e-learning at the conclusion of the study. The purpose of this phase is to explore if and how our dementia prevention e-learning influences participants' knowledge, intentions and health behaviours related to dementia risk. The investigators will also engage in participatory co-design with community partners using focus groups to determine pragmatic ways to effectively disseminate e-learning programs to support knowledge about dementia and preventative measures within equity-deserving groups.

Conditions

Dementia Prevention

Keywords

web-based intervention; knowledge translation; clinical trial; education and training; alzheimer disease; caregiver; dementia; internet

Outcome Measures

Primary Outcomes (1)

• 1. Knowledge change (custom 15-item knowledge questionnaire related to key dementia prevention modifiable risk factors

  A custom 15-item knowledge questionnaire (multiple true-false response) to measure change related to key dementia prevention modifiable risk factors. Items are pulled from other validated surveys (i.e., Dementia Knowledge Assessment Scale) and key dementia prevention modifiable risk factors.

  0 weeks, 4 weeks, 12 weeks

Secondary Outcomes (2)

• Intentions change (custom 10-item intentions questionnaire related to key dementia prevention modifiable risk factors)

  0 weeks, 4 weeks, 12 weeks

• Behaviour change related to dementia prevention (custom 42-item health behaviours questionnaire)

  0 weeks, 4 weeks, 12 weeks

Other Outcomes (2)

• Intervention adherence (time spent)

  4 weeks

• Participant satisfaction

  4 weeks

Study Arms (2)

Education Intervention

EXPERIMENTAL

Participants in the intervention group will be provided e-learning about dementia prevention and promoting brain health, consisting of following components: 1. One multimedia e-learning lesson on promoting brain health and preventing dementia; 2. A series of 12 'micro-learning' emails (3 emails/week) with small segments of content to reinforce the material from the lesson. 3. Curated resources related to dementia risk factors

Behavioral: Education Intervention

Education Control

ACTIVE COMPARATOR

Participants in the control group will be provided e-learning about mild cognitive impairment, consisting of following components: 1. One multimedia e-learning lesson on mild cognitive impairment; 2. A series of 12 'micro-learning' emails (3 emails/week) with small segments of content to reinforce the material from the lesson. 3. Curated resources related to mild cognitive impairment

Behavioral: Education Control

Interventions

Education Intervention BEHAVIORAL

Participants in the intervention group will be provided e-learning about dementia prevention and promoting brain health, consisting of following components: 1. One multimedia e-learning lesson on promoting brain health and preventing dementia; 2. A series of 12 'micro-learning' emails (3 emails/week) with small segments of content to reinforce the material from the lesson. 3. Curated resources related to dementia risk factors

Education Intervention

Education Control BEHAVIORAL

Participants in the control group will be provided e-learning about mild cognitive impairment, consisting of following components: 1. One multimedia e-learning lesson on mild cognitive impairment; 2. A series of 12 'micro-learning' emails (3 emails/week) with small segments of content to reinforce the material from the lesson. 3. Curated resources related to mild cognitive impairment

Education Control

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• No prior diagnosis of dementia
• Live in Canada
• years of age and over
• Good command of the English language
• Access to email and internet
• Comfortable using email and internet, and
• Ability to grant online informed consent

You may not qualify if:

• Prior diagnosis of dementia
• Lives outside of Canada
• Not 16 years of age or over
• Does not speak English,
• Does not have access to email or internet
• Is not comfortable using email of internet
• Does not grant informed consent

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

McMaster University

Hamilton, Ontario, L8S4L8, Canada

Location

MeSH Terms

Conditions

Alzheimer Disease; Dementia

Interventions

Early Intervention, Educational

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Child Health Services; Community Health Services; Health Services; Health Care Facilities Workforce and Services; Preventive Health Services

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Efforts will be made to blind participants to their allocation group (intervention or control). To do this, we will ensure that promotional advertisements do not contain logos or direct website links. The informed consent form will not contain the exact outcome measures or the title of the intervention. To the best of our abilities, allocation concealment will be aided by referring to the intervention as 'e-learning about cognitive impairment and dementia prevention', without biasing participants to study hypotheses or study design.
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 28, 2025
• First Posted: April 4, 2025
• Study Start: June 1, 2025
• Primary Completion: January 29, 2026
• Study Completion: January 29, 2026
• Last Updated: February 2, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)