NCT06901635

Brief Summary

Aging is a natural, universal and inevitable process seen in all living things. With aging, structural and functional irreversible degenerative changes occur in molecules, cells, tissues, organs and systems in living organisms. These changes, which extend from cells to systems in aging, may cause limitations in the functions necessary for elderly individuals to maintain their daily life activities such as walking, balance, coordination, visual and auditory skills, cognitive skills and dexterity. WHO defines old age as the period between 65-74 years of age as young old age, 75-84 years of age as middle-aged, and 85 years and older as old age (old age). Manual dexterity is the ability to move an object in a desired manner and is necessary to carry out activities of daily living. Decreases in dexterity may occur with aging, which leads to limitation of activities of daily living. Impaired dexterity leads to a progressive deterioration in the performance of activities of daily living that require the use of the hands. Therefore, the ability of older adults to live comfortably and independently is negatively affected. Numerous factors such as loss of grip strength, sensory disabilities, decreased vision, neuro-muscular problems and cognitive decline can lead to impaired dexterity in older adults. It has been shown that there is a further decline in dexterity with increasing age. One of the reasons affecting manual dexterity in the elderly is cognitive functions. Cognitive functions are a set of functions that enable the perception and understanding of all kinds of inputs received from the sensory organs. These functions include alertness, attention, memory, executive functions, planning, abstraction, language skills, time-space orientation and arithmetic. As with all physiological structures, cognitive functions are also impaired with aging. As age advances, impairments in cognitive functions become more noticeable. The term Dual Task (DT) refers to the ability to perform a cognitive and a motor task simultaneously. The addition of a concurrent cognitive task while performing a motor task often leads to impairment in motor task performance, referred to as the dual task effect (DTE) or dual task cost (DTC). Motor control and executive function are key elements of IG ability, and both are negatively affected by the aging process. Many of the activities of daily living of older adults require dual tasks, such as reading while walking or talking while using cutlery. Therefore, the ability to perform IG is essential for older adults to maintain functional independence. In previous studies, it was observed that when a second cognitive task was given while performing a motor task, motor task and cognitive task decreased; however, the effects of different cognitive tasks on manual dexterity motor task and the difference between young elderly (65-74) and middle-aged (75-84) were not examined. The aim of this study is to examine the effects of cognitive tasks that affect different cognitive functions such as attention, memory and executive functions on the dexterous motor task and to evaluate and compare the differences in two different elderly groups (young and middle-aged). Our study is of great importance in terms of evaluating which cognitive functions are affected during a dual task in elderly individuals and how much dexterity is affected by these functions. Since our study is to obtain data from a certain group in a certain period of time, the type of the research was determined as a cross-sectional study. There are dependent and independent variables in the study. The study aims to examine the effect of different cognitive dual tasks added to a motor task requiring manual dexterity on manual dexterity in geriatric individuals in two different age groups. In this context, the independent variables in the study are the type of cognitive task and age. In total, 4 different cognitive tasks were determined. The dependent variable is dexterity performance. The extent to which dexterity will be affected by 4 different cognitive task types and age will be examined.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 2, 2024

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

March 23, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 30, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 23, 2025

Completed
Last Updated

June 26, 2025

Status Verified

April 1, 2025

Enrollment Period

1.1 years

First QC Date

March 23, 2025

Last Update Submit

June 23, 2025

Conditions

Keywords

hand dexteritycognitive functiondual task

Outcome Measures

Primary Outcomes (1)

  • Box and Block Test

    The Box and Block Test is a quick, simple and inexpensive test that can be used in various populations to measure unilateral gross manual dexterity. The box and block test consists of a wooden box divided into two compartments by a board and 150 wooden blocks of 2.5 cm3. In the box block test, the person is asked to move the maximum number of blocks one by one from one compartment of the box to the other compartment of equal size within 60 seconds. A trial period of 15 seconds is allowed before starting the test. When placing the blocks in the other compartment, the participant's fingertips must cross the vertical plane of the compartment. The box block test has high reliability in the elderly population. It also has high reliability among manual dexterity assessors and has good criterion construct validity

    30 second

Secondary Outcomes (4)

  • COGNITIVE TASKS(Executive Functions)

    30 second

  • COGNITIVE TASK (Working Memory )

    30 second

  • COGNITIVE TASKS (Attention)

    30 second

  • COGNITIVE TASKS(Memory)

    30 second

Study Arms (2)

Healthy individuals aged 65-74 years

OTHER

Box and Block test was used to evaluate the manual dexterity of the participants. Cognitive tasks were given as secondary to the Box and Block test to evaluate the participants' Dual Task performance. In our study, 4 different secondary cognitive tasks were used.

Other: Dual Task

Healthy individuals aged 75-84 years

OTHER

Box and Block test was used to evaluate the manual dexterity of the participants. Cognitive tasks were given as secondary to the Box and Block test to evaluate the participants' Dual Task performance. In our study, 4 different secondary cognitive tasks were used.

Other: Dual Task

Interventions

In our study, manual dexterity and cognitive task performance during a dual task will be evaluated. Box and Block Test was used to assess dexterity and 4 different cognitive functions were used as cognitive tasks. Previous studies used one or two cognitive tasks when examining the relationship between cognitive task and dexterity performance during a dual task. This study will examine the effect of different cognitive tasks such as attention, memory, executive functions and working memory on the motor task requiring dexterity during a dual task.

Healthy individuals aged 65-74 yearsHealthy individuals aged 75-84 years

Eligibility Criteria

Age65 Years - 84 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • The participant was determined to be between the ages of 65-84, to be able to cooperate, and to have no obstacle to vision and hearing problems.

You may not qualify if:

  • The participant had any neurological, rheumatologic and noromuscular disease that would affect the dexterity of the participant, the Mini mental test was below 24, the participant had a hand use problem after any hand injury.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Marmara University

Istanbul, Istanbul, 3400, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 23, 2025

First Posted

March 30, 2025

Study Start

April 2, 2024

Primary Completion

April 30, 2025

Study Completion

June 23, 2025

Last Updated

June 26, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

"This study does not plan to share individual participant data due to ethical and privacy considerations."

Locations