The Association Between Residual Neuromuscular Block Risk Prediction Score and the Train-of-Four Ratio

NCT06899048 | Recruiting DMC

• 1 other identifier: 04-2025-201158
• Study Type: observational
• Target: 91
• Locations: 1 country
• Sites: 1

Brief Summary

evaluate the degree of association, and the predictive accuracy of the REPS (as a predictive tool) compared with the TOFr as a quantitative assessment tool for (rNMB) in surgical patients in the early postoperative phase. The TOFr will be measured at 0, 15, 30, 45, and 60 min after extubation.

Conditions

Muscle Relaxants

Outcome Measures

Primary Outcomes (1)

• correlation between residual neuromuscular block risk prediction score and train of four

  1 hour

Interventions

residual neuromuscular block risk prediction score DIAGNOSTIC_TEST

it is a clinical tool designed to estimate the likelihood of residual neuromuxcular blockade in postoperative patients

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who will be scheduled to undergo elective surgical procedures requiring the use of neuromuscular blocking drugs.

You may qualify if:

• Age group 18-65 years old
• Both genders
• Patients with American Society of Anesthesiologist physical status classification of 1 or 2.

You may not qualify if:

• Patients who are less than 18 years old or more than 65 years old.
• Patients with planned scheduled recovery in the intensive care unit or if more than 10 minutes had elapsed since tracheal extubation until NMB monitoring at the PACU.
• Patients on medications that interfere with muscle activity.
• Known allergy to neuromuscular blocking agents.
• Pregnancy or suspected pregnancy.
• Neuro-muscular diseases.
• Patients refusing to participate in the study.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University Hospitals

Asyut, 71111, Egypt

RECRUITING

MeSH Terms

Conditions

Muscle Hypotonia

Condition Hierarchy (Ancestors)

Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Mahmoud A Faisal, Dr

CONTACT

01004391577; dr_mahmoudfaisal@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: March 21, 2025
• First Posted: March 27, 2025
• Study Start: August 1, 2024
• Primary Completion: October 1, 2025
• Study Completion: April 1, 2026
• Last Updated: March 27, 2025

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)