"Stump-First" Approach in Laparoscopic Appendectomy

NCT06897709 | Completed

• 1 other identifier: 10/05/2023, numbered 2023/61
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Objective: This study aims to compare the standard laparoscopic appendectomy with the "Stump-First Approach" technique in patients diagnosed with acute appendicitis in terms of intraoperative and postoperative complications that may occur (injury, intra-abdominal abscess, postoperative fever, and infection parameters).

Conditions

Acute Appendicitis; Acute Appendicitis with Appendix Abscess

Keywords

appendectomy; laparoscopic appendectomy; surgical tecnic

Outcome Measures

Primary Outcomes (1)

• The number of participants compared in infection status

  The groups were compared in infection status (WBC, CRP, additional antibiotic requirements)

  1 year

Study Arms (2)

Group 1: underwent laparoscopic appendectomy using the standard approach

ACTIVE COMPARATOR

In Group 1, as part of the standard approach, the mesoappendix was initially ligated using LigaSure. After visualizing the base of the appendix, two hemoclips were applied on the stump side and one hemoclip on the appendix side. The tissue between was then divided with scissors, and the appendix was removed from the abdomen through the trocar in the umbilicus within an endobag.

Procedure: Classic Approach in Laparoscopic Appendectomy

Group 2 underwent laparoscopic appendectomy using the Stump-First Approach

ACTIVE COMPARATOR

Group 2, the cecal appendix was identified, and a window was created at the base of the appendix between the mesoappendix and the appendiceal wall. Two hemoclips were applied on the stump side, and one hemoclip on the appendix side. The tissue between was then divided with scissors. Finally, the mesoappendix was divided using LigaSure and the appendix was removed from the abdomen through the trocar in the umbilicus within an endobag

Procedure: Stump first Approach in Laparoscopic Appendectomy

Interventions

Classic Approach in Laparoscopic Appendectomy PROCEDURE

underwent laparoscopic appendectomy using the standard approach

Group 1: underwent laparoscopic appendectomy using the standard approach

Stump first Approach in Laparoscopic Appendectomy PROCEDURE

Stump first Approach in Laparoscopic Appendectomy

Group 2 underwent laparoscopic appendectomy using the Stump-First Approach

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Acute appendicitis

You may not qualify if:

• exist of pregnancy, exist of cancer

Sponsors & Collaborators

• Izmir City Hospital: lead

Study Sites (1)

İzmir City Hospital

Izmir, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Appendicitis

Condition Hierarchy (Ancestors)

Intraabdominal Infections; Infections; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Cecal Diseases; Intestinal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asosc. prof

Study Record Dates

• First Submitted: February 5, 2025
• First Posted: March 27, 2025
• Study Start: April 1, 2023
• Primary Completion: May 15, 2024
• Study Completion: May 15, 2024
• Last Updated: March 27, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)