NCT06897332

Brief Summary

With advances in technology, virtual reality (VR) is increasingly used in various fields, including rehabilitation, motor learning, and neuroscience. Its ability to provide controlled, immersive, and interactive environments makes it a valuable tool for training and assessment. However, despite its growing adoption, limited evidence exists on how cortical activation in VR compares to real-world conditions. Moreover, brain cortical activity during motor tasks, such as manual dexterity tasks, remains underexplored. This study aims to compare brain cortical activity in real and immersive virtual reality settings during a manual dexterity task. Secondary objectives include:

  • Examining the relationship between brain cortical activity and kinematics in both conditions.
  • Comparing brain cortical activity between hand-tracking and controller-based interactions.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 13, 2025

Completed
7 days until next milestone

Study Start

First participant enrolled

March 20, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 26, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2025

Completed
Last Updated

March 26, 2025

Status Verified

March 1, 2025

Enrollment Period

3 months

First QC Date

March 13, 2025

Last Update Submit

March 20, 2025

Conditions

BrainVirtual RealityEEGfNIRSManual Dexterity

Outcome Measures

Primary Outcomes (1)

  • Brain cortical activity

    Measures of brain cortical activity using EEG/fNIRS

    Baseline (at rest: before task performance) and Day 1 (during each of the three task performances within the single study session)

Secondary Outcomes (6)

  • Average speed

    Day 1 (during each of the three task performances within the single study session)

  • Maximal movement speed

    Day 1 (during each of the three task performances within the single study session)

  • Movement smoothness

    Day 1 (during each of the three task performances within the single study session)

  • Variation of velocity

    Day 1 (during each of the three task performances within the single study session)

  • Average distance between thumb and other fingers

    Day 1 (during each of the three task performances within the single study session)

  • +1 more secondary outcomes

Study Arms (1)

Healthy individuals

Behavioral: Real-world manual dexterity taskBehavioral: Immersive virtual reality with controllersBehavioral: Immersive virtual reality with hand-tracking

Interventions

Real-world manual dexterity taskBEHAVIORAL

Participants will perform a manual dexterity task involving the displacement of physical cubes

Healthy individuals
Immersive virtual reality with controllersBEHAVIORAL

Participants will perform a manual dexterity task in an immersive virtual reality environment, requiring them to move virtual cubes using controllers

Healthy individuals
Immersive virtual reality with hand-trackingBEHAVIORAL

Participants will perform a manual dexterity task in an immersive virtual reality environment, requiring them to move virtual cubes using the hand-tracking technology

Healthy individuals

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants will be recruited through word-of-mouth within the Belgian population

You may qualify if:

  • Age over 18 years old
  • Normal-to-corrected vision
  • Ability to understand simple instructions

You may not qualify if:

  • History of seizure
  • Recent participation (within the last three months) in a study involving a manual dexterity task in immersive virtual reality
  • Neurologic or orthopaedic pathology potentially affecting upper extremity movement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Neuro Musculo Skeletal Lab

Brussels, Brussels Capital, 1200, Belgium

Location

Study Officials

  • Thierry Lejeune, MD, PhD

    Cliniques universitaires Saint-Luc UCL

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gauthier Everard, PT, PhD

CONTACT

+32 472 500 158gauthier.everard@uclouvain.be

Thérèse Ntabuhashe Bibentyo, Er, PhD student

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 13, 2025

First Posted

March 26, 2025

Study Start

March 20, 2025

Primary Completion

June 30, 2025

Study Completion

June 30, 2025

Last Updated

March 26, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations

BE(1)