Culturally Adapted Cognitive Behavior Therapy Based Guided Self-help Manual for Schizophrenia Spectrum Disorder

NCT06895421 | Completed DMC

• 1 other identifier: Punjab University PHD thesis
• Study Type: interventional
• Target: 170
• Locations: 1 country
• Sites: 1

Brief Summary

The study evaluated the effectiveness of a culturally adapted Cognitive Behaviour Therapy for Psychosis (CBTp) Guided Self-Help (CBTp-GSH) intervention. It involved three phases: a qualitative study for cultural adaptation, a Randomized Controlled Trial (RCT) to test its efficacy against standard treatment, and an assessment of clinician training in applying the intervention. The findings showed that the culturally adapted CBTp-GSH was effective for individuals with Schizophrenia Spectrum Disorder, emphasizing the need for culturally sensitive therapy materials and proper clinician training.

Conditions

Receives Treatment As Usual; Receives Culturally Adapted CBTp GSH; Schizophrenia Disorders

Keywords

Schizophrenia Spectrum Disorder, culturally adapted, Guided Self-Help, RCT

Outcome Measures

Primary Outcomes (1)

• POSITIVE AND NEGATIVE SYMPTOM SCALE

  Positive and negative symptom scale was administered on pre and post level to measure the severity of symptoms High score indicates the worse outcome Lower score indicates better outcome

  8 TO 12 WEEKS

Study Arms (2)

Group 1: Receives culturally adapted CBTp- GHS plus treatment as usual.

EXPERIMENTAL

Participants receive culturally adapted Cognitive Behaviour Therapy for Psychosis-based Guided Self-Help.

Group 2: Receives Treatment As Usual (TAU).

ACTIVE COMPARATOR

TAU Arm: Participants receive standard treatment as usual.

Drug: Treatment as usual

Interventions

Cognitive behavior therapy based guided self help manual for psychosis plus treatment as usual BEHAVIORAL

The Cognitive Behavior Therapy-Based Guided Self-Help (CBTp-GSH) manual is a structured intervention designed specifically for individuals with psychosis, particularly those diagnosed with Schizophrenia Spectrum Disorders. This manual offers a culturally adapted approach, providing participants with tools and strategies rooted in Cognitive Behavioral Therapy (CBT) principles, tailored to be delivered through guided self-help.

Treatment as usual DRUG

anti psychotic drugs which they are already using

Group 2: Receives Treatment As Usual (TAU).

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Clients who could read and write had a minimum of 8th grade education.
• Clients who were able to engage with a mental health professional.
• Both inpatients and outpatients with a diagnosis of Schizophrenia or any Schizophrenia Spectrum Disorder, according to the DSM-V(American Psychiatric Association 2000), was included in the study.
• Client aged 18 to 60 years was included in the research.

You may not qualify if:

• Clients with co-morbid conditions such as alcohol or substance dependence, organic
• Brain syndrome, learning disability or high levels of disturbed behavior were excluded from the research. Client with high risk of suicide or homicide based on clinical impression was excluded from the research.

Sponsors & Collaborators

• University of the Punjab: lead

Study Sites (1)

University of the Punjab

Lahore, Pakistan

Location

MeSH Terms

Conditions

Schizophrenia

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Psychologist Punjab Institute of Mental Health, Lahore, Pakistan

Study Record Dates

• First Submitted: August 26, 2024
• First Posted: March 26, 2025
• Study Start: October 16, 2023
• Primary Completion: May 5, 2024
• Study Completion: August 12, 2024
• Last Updated: March 26, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)