Impact of Perioperative Nutritional Status and Management in the Context of Resectable Pancreatic Adenocarcinoma

NCT06893536 | Recruiting

• 1 other identifier: 9062
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Patients with pancreatic adenocarcinoma are frequently in a situation of malnutrition, in a context of functional alteration of the digestive tract, and hypercatabolism. As a result, nutritional support is frequently necessary perioperatively, but currently does not follow a specific protocol, and without coordination. It then appears the need to evaluate the prevalence of malnutrition, its impact on perioperative morbidity and mortality, and current management methods. Depending on the findings, subsequent interventional studies will be carried out on the subject, exploring the different modalities of artificial nutrition.

Conditions

Pancreatic Adenocarcinoma

Keywords

Pancreatic Adenocarcinoma; Digestive tract; Hypercatabolism; Malnutrition,

Outcome Measures

Primary Outcomes (1)

• Study of the Severity of Perioperative Malnutrition in Pancreatic Adenocarcinoma

  The CCI score measures a patient's postoperative outcome based on the number and severity of complications occurring on a scale of 0 to 100: 0: No complications 100: Death

  Up to 1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major subject (≥18 years old) with pancreatic adenocarcinoma authenticated by pathology and operated on in the visceral and digestive surgery department, NHC Strasbourg, during the period from January 1, 2018 to December 31, 2022

You may qualify if:

• Major subject (≥18 years old)
• Subject with pancreatic adenocarcinoma authenticated by pathology
• Subject candidate for curative surgical treatment
• Subject operated on in the visceral and digestive surgery department, NHC Strasbourg, during the period from January 1, 2018 to December 31, 2022
• Absence of written opposition in the subject's medical file to the reuse of their data for scientific research purposes.

You may not qualify if:

• Subject having expressed opposition to participating in the study
• Subject presenting a metastatic form or one not accessible to surgical treatment considered curative of pancreatic adenocarcinoma
• Subject under guardianship or curatorship
• Subje

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Chirurgie Viscérale et Digestive - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases

Central Study Contacts

Zineb CHERKAOUI, MD

CONTACT

33 3 69 55 13 15; zineb.cherkaoui@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 4, 2024
• First Posted: March 25, 2025
• Study Start: October 12, 2023
• Primary Completion: October 1, 2025
• Study Completion: October 12, 2025
• Last Updated: March 25, 2025

Record last verified: 2024-07

Locations

FR (1)