NCT02818829

Brief Summary

BACAP is a biobank dedicated to the pancreatic adenocarcinoma funded by institut national institue du cancer (INCa) and coordinated by Dr Barbara Bournet from Toulouse hospital. This base includes clinical data and biological samples such as blood, serum, plasma, saliva, DNA and RNA from tumors cells. The mission of this prospective project is to make available to the scientific community a clinical biological base from patients with pancreatic adenocarcinoma

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,700

participants targeted

Target at P75+ for all trials

Timeline
33mo left

Started May 2014

Longer than P75 for all trials

Geographic Reach
1 country

16 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
May 2014Jan 2029

Study Start

First participant enrolled

May 1, 2014

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

June 20, 2016

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 30, 2016

Completed
7.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 10, 2023

Completed
5.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2029

Expected
Last Updated

March 21, 2025

Status Verified

March 1, 2025

Enrollment Period

9.5 years

First QC Date

June 20, 2016

Last Update Submit

March 18, 2025

Conditions

Keywords

AdenocarcinomaEndoscopic ultrasonographyFine-needle aspirationBiomarkersEpidemiologyDNA tumors

Outcome Measures

Primary Outcomes (2)

  • Constitution of a transdisciplinary biobank with collection of biological samples with DNA

    The present project aims at creating, coordinating, animating a transdisciplinary multicentric national network, used to set up a clinical biological base (CBB) dedicated to the pancreatic adenocarcinoma

    Through the study completion, an average of 11 months

  • Constitution of a transdisciplinary biobank with collection of biological samples without DNA

    The present project aims at creating, coordinating, animating a transdisciplinary multicentric national network, used to set up a clinical biological base (CBB) dedicated to the pancreatic adenocarcinoma

    Through the study completion, an average of 11 months

Study Arms (1)

Cohort

Collection of biological samples

Other: Collection of biological samples

Interventions

Collection of biological samples including whole blood, serum, plasma, saliva, DNA and RNA from tumor cells, tissue from tumor biopsies, tissue from tumor and adjacent tissue of pancreas

Cohort

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with a pancreatic adenocarcinoma proven cytologically or histologically without any treatment

You may qualify if:

  • Patient eighteen years old
  • Histologically or cytologically confirmed pancreatic adenocarcinoma
  • Solid pancreatic mass explored with tomodensitometry or endoscopic ultrasonography fine-needle aspiration
  • Informed consent signed

You may not qualify if:

  • no informed consent
  • pregnancy women
  • no histologically or cytologically confirmed pancreatic adenocarcinoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (16)

University Hospital Bordeaux

Bordeaux, 33604, France

Location

Beaujon Hospital

Clichy, 92110, France

Location

University Hospital Lille

Lille, 59037, France

Location

University Hospital of Lille

Lille, 59037, France

Location

Centre Léon Bérard

Lyon, 69008, France

Location

Private Hospital Jean Mermoz

Lyon, 69008, France

Location

Hopital La Timone

Marseille, 13000, France

Location

Hospital Nord

Marseille, 13000, France

Location

Institut Regional du Cancer de Montpellier

Montpellier, 34000, France

Location

University Hospital Montpellier

Montpellier, 34000, France

Location

University Hospital of NICE

Nice, 06202, France

Location

Saint-Louis Hospital

Paris, 75010, France

Location

Clinique du Trocadero

Paris, 75016, France

Location

Pau Hospital

Pau, 64000, France

Location

University Hospital Toulouse

Toulouse, 31059, France

Location

Institut Gustave Roussy

Villejuif, 94805, France

Location

Related Publications (3)

  • Maulat C, Canivet C, Touraine C, Gourgou S, Napoleon B, Palazzo L, Flori N, Piessen G, Guibert P, Truant S, Assenat E, Buscail L, Bournet B, Muscari F, The Bacap Consortium. A New Score to Predict the Resectability of Pancreatic Adenocarcinoma: The BACAP Score. Cancers (Basel). 2020 Mar 25;12(4):783. doi: 10.3390/cancers12040783.

  • Frere C, Bournet B, Gourgou S, Fraisse J, Canivet C, Connors JM, Buscail L, Farge D; BACAP Consortium. Incidence of Venous Thromboembolism in Patients With Newly Diagnosed Pancreatic Cancer and Factors Associated With Outcomes. Gastroenterology. 2020 Apr;158(5):1346-1358.e4. doi: 10.1053/j.gastro.2019.12.009. Epub 2019 Dec 14.

  • Canivet C, Gourgou-Bourgade S, Napoleon B, Palazzo L, Flori N, Guibert P, Piessen G, Farges-Bancel D, Seitz JF, Assenat E, Vendrely V, Truant S, Vanbiervliet G, Berthelemy P, Garcia S, Gomez-Brouchet A, Buscail L, Bournet B; BACAP Consortium. A prospective clinical and biological database for pancreatic adenocarcinoma: the BACAP cohort. BMC Cancer. 2018 Oct 16;18(1):986. doi: 10.1186/s12885-018-4906-4.

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood, serum, plasma, saliva, DNA and RNA from tumor cells, tissue from tumor biopsie, tissue from tumor and adjacent tissue of pancreas

MeSH Terms

Conditions

Adenocarcinoma

Condition Hierarchy (Ancestors)

CarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasms

Study Officials

  • Barbara BOURNET, MD; PHD

    University Hospital, Toulouse

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 20, 2016

First Posted

June 30, 2016

Study Start

May 1, 2014

Primary Completion

November 10, 2023

Study Completion (Estimated)

January 1, 2029

Last Updated

March 21, 2025

Record last verified: 2025-03

Locations