Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses

NCT06892470 | Active Not Recruiting

• 1 other identifier: H2025-015-K-14-04
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective study aims to compare the visual outcomes following the implantation of two different types of multifocal intraocular lenses (IOLs) in highly myopic patients. The study will evaluate visual quality, refractive outcomes, and patient satisfaction using various visual assessment techniques and subjective satisfaction surveys.

Conditions

Cataract

Outcome Measures

Primary Outcomes (2)

• Defocus Curve

  The defocus curve is a tool used to assess visual acuity, particularly widely applied in evaluating the performance of presbyopia-correcting intraocular lenses (IOLs). Its principle involves placing a series of positive and negative lenses of varying diopters in front of the patient's eyes to simulate different distances from near to far, thereby assessing the patient's visual acuity (VA) at each simulated distance.

  Three months after operation

• Visual Questionnaire

  A visual questionnaire is a tool used to assess patients' visual function and quality of life. It typically includes a series of questions covering various aspects such as visual acuity at different distances (e.g., distance, intermediate, and near vision), dependency on glasses, and the impact of vision on the quality of life. By using a visual questionnaire, one can understand the actual visual experience and satisfaction of patients after the implantation of an intraocular lens.

  Three months after operation

Study Arms (2)

TNF Group:

Implantation of PanOptix trifocal IOL

Other: No intervention

ZFR Group:

Implantation of Tecnis Symfony ZFR00 extended depth of focus IOL (Johnson \& Johnson)

Other: No intervention

Interventions

No intervention OTHER

No intervention

TNF Group:; ZFR Group:

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals who undergo micro-incision cataract surgery and implantation of targeted intraocular lenses at the Hangzhou Branch of Wenzhou Medical University Eye Hospital.

You may qualify if:

• : Patients are older than 18 years
• : The axial length (AL) measured by IOLMaster 700 is ≥26 mm
• : No anterior or posterior segment pathology that could potentially compromise visual potential (such as glaucoma, myopic traction maculopathy, corneal leukoma, etc.).
• : Able to understand, cooperate, and complete all follow - ups

You may not qualify if:

• : History of amblyopia
• : Retinal detachment in the same eye or the fellow eye
• : Presence of multiple peripheral retinal degenerative changes
• : History of previous ocular surgery

Sponsors & Collaborators

• Wenzhou Medical University: lead

Study Sites (1)

Ophthalmology and Optometry Hos

Hanzhou, Zhejian, China

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens Diseases; Eye Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Vice president of Eye Hospital of Wenzhou Medical University

Study Record Dates

• First Submitted: March 21, 2025
• First Posted: March 24, 2025
• Study Start: March 1, 2025
• Primary Completion (Estimated): May 30, 2026
• Study Completion (Estimated): May 30, 2026
• Last Updated: March 24, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)