Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery

NCT06751342 | Active Not Recruiting

• 1 other identifier: psychophysical methods
• Study Type: observational
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

Using Psychophysics Methods for Quantitative Assessment of Sensory Binocular Imbalance After Cataract Surgery

Conditions

Cataract

Outcome Measures

Primary Outcomes (2)

• Perceptual Phase

  The perceptual phase when the interocular contrast between the two eyes is 1.

  Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.

• Ocular Dominance Index (ODI)

  The ratio of the total time spent by the observer reporting complete dominance of visual stimuli presented to the dominant or non-dominant eye.

  Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.

Study Arms (6)

Subjects with Unilateral Congenital Cataract Undergoing Surgery

Subjects with Bilateral Congenital Cataract Undergoing Surgery

Control Group of Children

Subjects with Comparable Degrees of Bilateral Age-Related Cataract

Subjects with Different Degrees of Bilateral Age-Related Cataracts

Subjects with Shallow Anterior Chambers in Both Eyes

Eligibility Criteria

• Age: 6 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Included in Eye Hospital of Wenzhou Medical University for "phacoemulsification combined with intraocular lens implantation"

You may qualify if:

• Ages between 6 and 90 years old, and the individual or legal guardian is capable of understanding and voluntarily signing an informed consent form;
• No history of ocular trauma or intraocular surgery, no physical or medical treatments have been undergone, and the clinical diagnosis in the medical records is age-related, congenital, or developmental cataract patients;
• Best-corrected visual acuity in both eyes is greater than 0.8 before the study, fusion ability is normal as checked by Worth's 4-dot test, and at least 1 month has passed since the last surgery;
• Good communication skills and the ability to understand and grasp the trial;
• No significant contraindications to surgery found in preoperative systemic and ocular examinations.

You may not qualify if:

• Patients with traumatic or complex cataracts;
• Those diagnosed with glaucoma before or after surgery;
• Individuals with a history of intraocular surgery (such as vitrectomy) or laser treatment;
• Exclude those with severe ocular comorbidities (including microphthalmia, aphakia, anterior segment dysgenesis, uveitis, optic nerve dysplasia, retinopathy of prematurity, congenital glaucoma, etc.) and severe systemic comorbidities (including syndromes affecting connective tissue function, such as Marfan syndrome, homocystinuria, or Down syndrome, severe birth defects, and epilepsy);
• Any systemic diseases related to the eyes, such as rheumatic immune diseases;
• Those with surgical records indicating any severe intraoperative complications during cataract surgery;
• Individuals who cannot cooperate with the examination.

Sponsors & Collaborators

• Wenzhou Medical University: lead

Study Sites (1)

Ophthalmology and Optometry Hospital, Wenzhou

Wenzhou, Zhejiang, 325027, China

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens Diseases; Eye Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Vice president of Eye Hospital of Wenzhou Medical University

Study Record Dates

• First Submitted: December 20, 2024
• First Posted: December 27, 2024
• Study Start: December 1, 2024
• Primary Completion: December 30, 2025
• Study Completion: December 30, 2025
• Last Updated: December 27, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)