NCT06887439

Brief Summary

This prospective study aims to determine the relationship between the EASIX score and mortality and prognosis in sepsis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2024

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

March 14, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 20, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

January 21, 2026

Status Verified

January 1, 2026

Enrollment Period

1.4 years

First QC Date

March 14, 2025

Last Update Submit

January 16, 2026

Conditions

SepsisSeptic ShockSeptic Syndrome

Keywords

sepsisseptic shockendothelium

Outcome Measures

Primary Outcomes (1)

  • mortality

    The primary finding of the study was 28-day mortality after sepsis diagnosis

    28 days

Secondary Outcomes (2)

  • Septic shock

    28 days

  • Acute kidney injury

    28 days

Study Arms (1)

sepsis group

Adult patients (≥18 years old) diagnosed with sepsis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients (≥18 years old) diagnosed with sepsis were included.

You may qualify if:

  • Patients diagnosed with sepsis during intensive care admission or admitted to intensive care with a diagnosis of sepsis
  • All patients over the age of 18

You may not qualify if:

  • Patients under the age of 18
  • Patients with a history of multiple intensive care admissions
  • Patients who died within 24 hours of diagnosis
  • Patients diagnosed with CRF or currently treated for ARF
  • Patients with deficient serum creatinine, LDH and platelet values at the time of diagnosis Patients for whom consent could not be obtained from themselves or their relatives

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sisli etfal research and training hospital

Istanbul, 34371, Turkey (Türkiye)

Location

MeSH Terms

Conditions

SepsisShock, SepticToxemia

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and SymptomsShock

Study Officials

  • AYSE SURHAN CINAR

    şişli etfal eğitim araştırma hastanesi

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
18 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associate professor

Study Record Dates

First Submitted

March 14, 2025

First Posted

March 20, 2025

Study Start

June 1, 2024

Primary Completion

November 1, 2025

Study Completion

December 1, 2025

Last Updated

January 21, 2026

Record last verified: 2026-01

Locations

TU(1)