Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis

NCT06884839 | Recruiting

• 1 other identifier: 1267/09/2024
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the tumor deposits in colorectal cancer and its prognostic value in survival and metastasis

Conditions

Tumor Deposits; Colorectal Cancer; Prognosis; Survival; Metastasis

Outcome Measures

Primary Outcomes (1)

• Patients' overall survival

  Patients' overall survival (OS) is defined as from colorectal cancer (CRC) diagnosis to death.

  2 years postoperatively

Secondary Outcomes (1)

• Distant metastasis

  2 years postoperatively

Study Arms (1)

Therapeutic resection group

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Procedure: Therapeutic resection

Interventions

Therapeutic resection PROCEDURE

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Therapeutic resection group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This prospective and retrospective study will be conducted on 30 patients with colorectal cancer.

You may qualify if:

• Age above 18 years old.
• Both sexes.
• All Colorectal cancer patients From Stage I to III Colorectal cancer with pathologically positive Tumor deposits.

You may not qualify if:

• Patient took neoadjuvant therapy.
• No information available on tumor deposits.
• Colorectal cancer is not the only primary cancer.
• Patients with incomplete information about follow-up.

Sponsors & Collaborators

• Minia University: lead

Study Sites (1)

Minia University

Minya, 61611, Egypt

RECRUITING

MeSH Terms

Conditions

Extranodal Extension; Colorectal Neoplasms; Neoplasm Metastasis

Condition Hierarchy (Ancestors)

Neoplastic Processes; Neoplasms; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Central Study Contacts

Abdelrahman M Salah, MD

CONTACT

00201064746493; Abdelrahman.salah@mu.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of General Surgery, Faculty of Medicine, Minia University, Minia, Egypt.

Study Record Dates

• First Submitted: March 13, 2025
• First Posted: March 19, 2025
• Study Start: August 1, 2022
• Primary Completion: August 1, 2025
• Study Completion: August 1, 2025
• Last Updated: March 19, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)