NCT06884566

Brief Summary

This crossover-design study examines the acute effect of taurine on trained individuals aged 18-40 on strength and power outputs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 7, 2025

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 21, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 21, 2025

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

January 23, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 19, 2025

Completed
Last Updated

March 19, 2025

Status Verified

January 1, 2025

Enrollment Period

14 days

First QC Date

January 23, 2025

Last Update Submit

March 13, 2025

Conditions

Taurine

Keywords

TaurinePowerStrenghtExercise

Outcome Measures

Primary Outcomes (10)

  • Maximal Isometric strength in kilograms assessed via handgrip test

    Day 1

  • Relative Isometric strength in kilograms assessed via handgrip test

    Day 1

  • Maximal Instantaneous power generation in W/kg assessed via vertical jump height test.

    Day 1

  • Average Instantaneous power generation in W/kg assessed via vertical jump height test.

    Day 1

  • Peak power in Watts assessed via the Wingate Anaerobic test

    Day 1

  • Maximal Isometric strength in kilograms assessed via handgrip test

    After 48 hours

  • Relative Isometric strength in kilograms assessed via handgrip test

    After 48 hours

  • Maximal Instantaneous power generation in W/kg assessed via vertical jump height test.

    After 48 hours

  • Average Instantaneous power generation in W/kg assessed via vertical jump height test.

    After 48 hours

  • Peak power in Watts assessed via the Wingate Anaerobic test

    After 48 hours

Study Arms (2)

Taurine supplementation

EXPERIMENTAL

Participants consumed 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink.

Dietary Supplement: Taurine supplementation

Placebo

PLACEBO COMPARATOR

Placebo was a 500ml sugar-free lemonade drink with nothing added

Dietary Supplement: Placebo

Interventions

Taurine supplementationDIETARY_SUPPLEMENT

For the intervention trials participants consumed the following in randomized order: 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink or placebo which was a sugar-free lemonade drink with nothing added, 60 minutes before the exercise protocols. Participants wore a nose plug during consumption to confirm that no taste differences were discernible between trials.

Taurine supplementation
PlaceboDIETARY_SUPPLEMENT

For the intervention trials participants consumed the following in randomized order: 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink or placebo which was a sugar-free lemonade drink with nothing added, 60 minutes before the exercise protocols. Participants wore a nose plug during consumption to confirm that no taste differences were discernible between trials.

Placebo

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • participants 18 - 40 years of age
  • physically active or recreationally active with consistent training more than 3 times per week for at least 6 months
  • non-smokers

You may not qualify if:

  • cardiovascular, respiratory or metabolic diseases
  • any musculoskeletal injury in the last six months
  • taking taurine and/or creatine supplementation in the past three months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Central Lancashire Cyprus

Larnaca, Pyla, 7080, Cyprus

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Efstathios Christodoulides, PhD

    https://www.uclancyprus.ac.cy/

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Lecturer

Study Record Dates

First Submitted

January 23, 2025

First Posted

March 19, 2025

Study Start

January 7, 2025

Primary Completion

January 21, 2025

Study Completion

January 21, 2025

Last Updated

March 19, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share

Locations

CY(1)