NCT06882889

Brief Summary

This study compares the hearing improvement effects of domestic hearing aids and imported hearing aids in 80 patients with moderate to severe and severe age-related hearing loss. Patients will be randomly assigned to either the experimental group (domestic hearing aids) or the control group (imported hearing aids) and will undergo a 30-minute trial. Pure Tone Average (PTA) and Speech Recognition Threshold (SRT) will be measured both before and after the trial. The improvements in PTA and SRT will be calculated.The market prices of the hearing aids and the degree of hearing improvement in decibels will be recorded. These data will be used to conduct a comprehensive cost-effectiveness analysis. After the trial, the International Outcome Inventory for Hearing Aids (IOI-HA) and the Abbreviated Profile of Hearing Aid Benefit (APHAB) will be used to assess the benefits of the hearing aids.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 24, 2024

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 11, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 19, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

August 13, 2025

Status Verified

August 1, 2025

Enrollment Period

10 months

First QC Date

February 11, 2025

Last Update Submit

August 12, 2025

Conditions

Keywords

Age-related hearing lossHearing AidsRandomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

  • Improvement in Pure Tone Average (ΔPTA)

    Improvement in Pure Tone Average (ΔPTA): The improvement in Pure Tone Average (ΔPTA) will be assessed by measuring the average of the lowest sound intensities detectable at 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz in the better ear of patients with moderate to severe and severe age-related hearing loss both before and after hearing aid fitting, using pure tone audiometry and sound field audiometry. These measurements will be recorded as pre-fitting PTA and post-fitting PTA. Improvement in Pure Tone Average (ΔPTA) = post-fitting PTA - pre-fitting PTA

    The initial assessment will be conducted prior to the use of the hearing aid, and the follow-up assessment will be performed 0.5 hours after the hearing aid is used.

Secondary Outcomes (4)

  • Improvement in Speech Recognition Threshold (ΔSRT)

    The initial assessment will be conducted prior to the use of the hearing aid, and the follow-up assessment will be performed 0.5 hours after the hearing aid is used.

  • International Outcome Inventory for Hearing Aids (IOI-HA)

    The assessment will be conducted only after the patient has used the hearing aid for 0.5 hours.

  • Abbreviated Profile of Hearing Aid Benefit (APHAB)

    The assessment will be conducted only after the patient has used the hearing aid for 0.5 hours.

  • Cost-Effectiveness Analysis (CEA):

    The assessment will be conducted only after the patient has used the hearing aid for 0.5 hours.

Study Arms (2)

The experimental group

EXPERIMENTAL

The experimental group will use domestic hearing aids.

Device: Domestic hearing aids

The control group

ACTIVE COMPARATOR

The control group will use imported hearing aids.

Device: Imported hearing aids

Interventions

The domestic hearing aids used in this study are from the Bigsound brand. Using domestic hearing aids for intervention, one first evaluates the patient's hearing condition through pure-tone audiometry. Subsequently, by thoroughly understanding the patient's hearing needs, lifestyle, and other relevant factors, the most suitable type and functions of hearing aids are selected to best meet the individual's specific situation.

The experimental group

The imported hearing aids used in this study are from the Phonak brand. Using imported hearing aids for intervention, one first evaluates the patient's hearing condition through pure-tone audiometry. Then, by thoroughly understanding the patient's hearing needs, lifestyle, and other relevant factors, the most suitable type and functions of hearing aids are selected to best meet the individual's specific situation.

The control group

Eligibility Criteria

Age60 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 60 years and ≤ 85 years;
  • Diagnosed with age-related hearing Loss, which is characterized by bilateral, symmetrical, and gradually progressive hearing loss primarily affecting high frequencies, along with a decline in speech recognition ability, as referenced in the "Expert Consensus on Diagnosis and Intervention of Age-Related Hearing Loss" (2019 edition);
  • Age-related hearing Loss is of moderate to severe or severe sensorineural hearing loss, with moderate to severe defined as 50 to \<65 dB HL, and severe defined as 65 to \<80 dB HL;
  • Chinese nationality, able to complete all assessments in the Chinese language;
  • Right-handed;
  • No significant neurological diseases, severe systemic diseases, family history of genetic disorders, or major psychiatric conditions;

You may not qualify if:

  • Inability to use hearing aids ;
  • Presence of dementia, Parkinson's disease, or other neurodegenerative diseases that may affect study compliance;
  • History of cerebrovascular accidents, stroke, epilepsy, or other central nervous system disorders;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sun Yat-sen Memorial Hospital of Sun Yat-sen University

Guangzhou, Guangdong, 5100000, China

RECRUITING

MeSH Terms

Conditions

PresbycusisHearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Yang Haidi, PhD

    SunYatSunU2H

    STUDY CHAIR

Central Study Contacts

Yang Haidi, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: The experimental group will use domestic hearing aids, and the control group will use imported hearing aids.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 11, 2025

First Posted

March 19, 2025

Study Start

October 24, 2024

Primary Completion

August 30, 2025

Study Completion

December 31, 2025

Last Updated

August 13, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations