Effect of Baseline Ferritin Level on Iron Status in Male Elite Youth Rowers

NCT06878040 | Completed DMC

• 1 other identifier: WIOSŁA2023
• Study Type: observational
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The data of 16 trained men from the Polish Youth National Rowing. All athletes presented as medically fit, with no underlying health problems. In this cohort, baseline serum ferritin levels were considered, and the athletes were divided into two groups:

1. 1.Serum ferritin \<75 ng/ml (SF\<75): n=9
2. 2.Serum ferritin \>75 ng/ml (SF\>75): n=7

Conditions

Inflammation; Iron Deficiency Anemias; Red Blood Cell

Outcome Measures

Primary Outcomes (12)

• Ferritin

  Concentration of ferritin \[ng/mL\]. ELISA method by the test manufacturer's instructions

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• Iron

  The iron level \[µg/dL\] will be determined using the colorimetric method on the SPECTROstar Nano reader.

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• Interleukin-6 (Il-6)

  Concentration of IL-6 \[ng/L\]. ELISA method by the test manufacturer's instructions

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• Hepcidin

  Concentration of hepcidin \[ng/mL\]. ELISA method by the test manufacturer's instructions

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• Transferrin

  Concentration of transferrin \[mg/mL\]. ELISA method by the test manufacturer's instructions

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology - RBC (Red Blood Cells)

  RBC (Red Blood Cells) \[106 × µL-1\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- HGB (Hemoglobin)

  HGB (Hemoglobin) \[g/dL\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- HCT (Hematocrit)

  HCT (Hematocrit) \[%\]determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- MCV (Mean Corpuscular Volume)

  MCV (Mean Corpuscular Volume)\[fl\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- MCH (Mean Corpuscular Hemoglobin)

  MCH (Mean Corpuscular Hemoglobin) \[pg\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- MCHC (Mean Corpuscular Hemoglobin Concentration)

  MCHC (Mean Corpuscular Hemoglobin Concentration) \[g x dL-1\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

• The Blood morphology- RDW (Red Blood cells Distribution Width)

  RDW (Red Blood cells Distribution Width) \[%\] determined on the MYTHIC 18 hematology analyzer (Orphee Medical, Geneva, Switzerland).

  At rest (before the test), directly after the test, and after a 1-hour recovery period.

Secondary Outcomes (7)

• Antropometric characteristic - height

  Day 1 after overall fast

• Antropometric characteristic - weight

  Day 1 after overall fast

• Food record - energy

  Day before the Day 1, in the morning at Day 1

• Food record - protein

  Day before the Day 1, in the morning at Day 1

• Food record - carobhydrates

  Day before the Day 1, in the morning at Day 1

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Youth National Rowing Team of Poland

You may qualify if:

• Training experience a minimum of five years
• Minimum training time per week 240 minute
• Membership in the Youth National Rowing Team of Poland
• Completion of the 2000m ergometer test on two test dates

You may not qualify if:

• Taking other supplements containing anthocyanin compounds during the study period or a month earlier
• Antibiotic therapy
• Health problems

Sponsors & Collaborators

• Poznan University of Physical Education: lead

Study Sites (1)

Poznań University of Physical Education,

Poznan, 61-871, Poland

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Eppendorf tubes with serum.

MeSH Terms

Conditions

Inflammation; Anemia, Iron-Deficiency

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Anemia, Hypochromic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Iron Deficiencies; Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 10, 2025
• First Posted: March 14, 2025
• Study Start: April 1, 2023
• Primary Completion: June 10, 2023
• Study Completion: June 10, 2023
• Last Updated: March 20, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)