Comparison of Immediate Implant Placement With Titanium Mesh Versus Collagen Membrane in Type II Socket:

NCT06875830 | Active Not Recruiting DMC

• 1 other identifier: PER5253015
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone. Aim: The aim of this study is to assess the buccal bone thickness after augmentation with titanium mesh and xenograft upon flapless immediate implant placement.

Conditions

Bone Augmentation; Badly Broken Maxillary Premolars Indicated for Extraction

Outcome Measures

Primary Outcomes (1)

• Buccal bone thickness

  assessment of the Buccal bone thickness in mm using CBCT

  at baseline, 6 and 12 months

Secondary Outcomes (2)

• Soft tissue thickness

  at baseline 6 and 12 months

• Keratinized tissue width

  at baseline, 6 and 12 months

Study Arms (2)

immediate implant with collagen membrane

ACTIVE COMPARATOR

immediate implant placement will be done and augmentation of the buccal bone will be done with xenograft and collagen membrane

Procedure: collagen membrane

immediate implant with titanium mesh

ACTIVE COMPARATOR

immediate implant placement will be done and augmentation of the buccal bone will be done with xenograft and titanium mesh

Procedure: titanium mesh

Interventions

collagen membrane PROCEDURE

augmentation of the buccal plate of bone with xenograft and collagen membrane

immediate implant with collagen membrane

titanium mesh PROCEDURE

augmentation of the buccal plate of bone with xenograft and titanium mesh

immediate implant with titanium mesh

Eligibility Criteria

• Age: 21 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients who have at least one remaining root or badly decayed tooth in anterior maxilla.
• Systemically free patients (American Society of Anesthesiologists I; ASA I)
• Patients aged from 21 to 50 years old
• Buccal bone partial deficiency (extraction socket type II)
• Good oral hygiene
• Accepts the follow-up period (cooperative patients)
• Patient accepts to provides an informed consent

You may not qualify if:

• Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits such as bruxism
• Smokers
• Pregnant and lactating females

Sponsors & Collaborators

• Misr International University: lead

Study Sites (1)

Faculty of oral & dental Medicine,Misr international University

Cairo, 123456, Egypt

Location

Study Officials

• ahmed H Farid, Masters

  Assistant lecturer

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 9, 2025
• First Posted: March 13, 2025
• Study Start: March 6, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: January 13, 2026

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)