Soft Tissue Healing After Tooth Extraction
Assessment of Amnion Membrane Versus Chorion Membrane for Soft Tissue Healing After Tooth Extraction; a Randomized Clinical Trial
1 other identifier
interventional
190
1 country
1
Brief Summary
Statement of the problem: Tooth extraction results in hard and soft tissue loss which complicates prosthodontic rehabilitation, So different techniques of alveolar ridge preservation should be done to maintain hard and soft tissue dimensions. Aim: The aim of this study is to compare the effect of amnion membrane versus chorion membrane on soft tissue healing among socket preservation procedure.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 7, 2025
CompletedFirst Submitted
Initial submission to the registry
February 14, 2025
CompletedFirst Posted
Study publicly available on registry
February 19, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 7, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2025
CompletedFebruary 19, 2025
January 1, 2025
6 months
February 14, 2025
February 14, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Soft tissue healing
Surface area/intraoral scanner
every day for the first week, day after day second week, once in third and fourth week
Secondary Outcomes (1)
Healing index
every day for the first week, day after day second week, once in third and fourth week
Study Arms (2)
Amnion membrane
ACTIVE COMPARATORthe amnion membrane tucked over the extraction socket then the socket plug will be maintained in place with approximating sutures using 5-0 resorbable suture material
Chorion membrane.
ACTIVE COMPARATORchorion membrane (Bioxclude , Snoasis Medical , USA) tucked over the extraction socket then the socket plug will be maintained in place with approximating sutures using 5-0 resorbable suture material.
Interventions
the amnion membrane tucked over the extraction socket then the socket plug will be maintained in place with approximating sutures using 5-0 resorbable suture material
chorion membrane tucked over the extraction socket then the socket plug will be maintained in place with approximating sutures using 4-0 resorbable suture material.
Eligibility Criteria
You may qualify if:
- \. Patients who need simple extraction not indicated for immediate implant placement.
You may not qualify if:
- Patients with inability or anticipated failure to maintain adequate oral hygiene.
- Pregnant or breast-feeding mothers.
- Any medical condition or therapy that can affect healing.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
faculty of oral and dental medicine , Suez university
Suez, Suez Governorate, 123456, Egypt
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Masking Details
- blinding of outcome assessors and participants will be achieved as the different outcomes will be assessed for all groups by assessors other than the researchers doing the procedures.
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 14, 2025
First Posted
February 19, 2025
Study Start
January 7, 2025
Primary Completion
July 7, 2025
Study Completion
August 1, 2025
Last Updated
February 19, 2025
Record last verified: 2025-01