NCT06871683

Brief Summary

The objective of this survey is to determine the safety and efficacy of the ClotTriever Thrombectomy System under daily clinical practice after marketing approval in Japan. This device was designated as a subject of use results evaluation at the time of application for manufacturing and marketing approval.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
31mo left

Started Feb 2025

Typical duration for all trials

Geographic Reach
1 country

13 active sites

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress32%
Feb 2025Dec 2028

Study Start

First participant enrolled

February 17, 2025

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

March 6, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 12, 2025

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2028

Expected
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

May 4, 2026

Status Verified

April 1, 2026

Enrollment Period

3 years

First QC Date

March 6, 2025

Last Update Submit

April 28, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Rate of Major Adverse Events

    Rate of Major Adverse Events \[All-cause mortality, Major bleeding, New symptomatic Pulmonary Embolism (PE) documented by Computed Tomography Pulmonary Angiography (CTPA), Rethrombosis of a Target Venous Segment\].

    Through 30 days post index procedure.

  • Technical Success

    Thrombus residual volume assessed by the the treating physician using pre- and post-procedure venography to evaluate the success of thrombus removal.

    During the index procedure

Study Arms (1)

Full Analysis Population

All subjects who the survey device entered their vasculature.

Device: ClotTriever® Thrombectomy System

Interventions

ClotTriever® Thrombectomy System use for treatment of patients with deep vein thrombosis with acute severe symptoms.

Full Analysis Population

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with deep vein thrombosis with acute severe symptoms (excluding postthrombotic syndrome) for whom the ClotTriever® Thrombectomy System was used. Patients will be enrolled until at least 100 subjects complete the follow-up period through 6 months.

This is an all-comers survey of all patients treated with ClotTriever® Thrombectomy System in Japan.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (13)

Chiba University Hospital

Chūō, Chiba, 260-8677, Japan

Location

Ota Memorial Hospital

Ōta, Gunma, 373-8585, Japan

Location

St. Marianna University Hospital

Kawasaki, Kanagawa, 216-8511, Japan

Location

National Cerebral and Cardiovascular Center

Suita, Osaka, 564-8565, Japan

Location

Asahikawa Medical Hospital

Asahikawa, 078-8510, Japan

Location

Asahi General Hospital

Chiba, 289-2511, Japan

Location

Nozaki Tokushukai Hospital

Daitō, 574-0074, Japan

Location

Shonan Kamakura

Kanagawa, 247-8533, Japan

Location

Kyoto Katsura Hospital

Kyoto, 615-8256, Japan

Location

Nara City Hospital

Nara, 630-8305, Japan

Location

Osaka Police Hospital

Osaka, 543-0042, Japan

Location

Mitsui Memorial Hospital

Tokyo, 101-8643, Japan

Location

Mie University

Tsu, 514-0102, Japan

Location

MeSH Terms

Conditions

Venous Thrombosis

Condition Hierarchy (Ancestors)

ThrombosisEmbolism and ThrombosisVascular DiseasesCardiovascular Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 6, 2025

First Posted

March 12, 2025

Study Start

February 17, 2025

Primary Completion (Estimated)

March 1, 2028

Study Completion (Estimated)

December 1, 2028

Last Updated

May 4, 2026

Record last verified: 2026-04

Locations