Evaluating the Use of Grip Exercises to Decrease Deep Vein Thrombosis in Adult Patients With PICC Lines
1 other identifier
interventional
2,500
1 country
2
Brief Summary
Patients who have a peripherally-inserted central catheter (PICC) placed are at a risk of developing a deep vein thrombosis (DVT). At TriHealth, approximately 2-4 patients per month who have a PICC placed experience a subsequent DVT. One innovative way to possibly mitigate the risk of DVTs is hand grip exercises. The current study will be the first study to evaluate hand grip exercises for the prevention of DVTs in adult patients hospitalized in the United States.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2023
Longer than P75 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 6, 2023
CompletedFirst Submitted
Initial submission to the registry
December 19, 2023
CompletedFirst Posted
Study publicly available on registry
April 17, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 30, 2027
February 17, 2026
February 1, 2026
3.7 years
December 19, 2023
February 12, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Deep vein thrombosis
Incidence of deep vein thrombosis
from PICC placement to PICC removal, up to 4 weeks
Study Arms (2)
Handgrip Exercise Group
EXPERIMENTALParticipants will be instructed to firmly grip and squeeze the ball for 10 seconds, relax for 10 seconds and repeat for 10 minutes. They will be instructed to do this 3 times per day.
Standard Care Group
NO INTERVENTIONParticipants will receive standard care that includes no instruction about conducting hand grip exercises.
Interventions
Participants will firmly grip and squeeze the ball for 10 seconds, relax for 10 seconds and repeat for 10 minutes. They will be instructed to do this 3 times per day.
Eligibility Criteria
You may qualify if:
- Had a PICC placed in the past 24 hours by the Vascular Access Team
- Patient is admitted to either Bethesda North Hospital or Good Samarian Hospital
You may not qualify if:
- Under 18 years old
- Does not speak English
- Unable to consent to involvement in the research study
- Has a bleeding disorder/diagnosis
- Has a severe limb disfunction whereby they would be unable to perform the grip exercises
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- TriHealth Inc.lead
Study Sites (2)
Good Samaritan Hospital
Cincinnati, Ohio, 45220, United States
Bethesda North Hospital
Cincinnati, Ohio, 45242, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Rachel Baker, PhD, RN
TriHealth Nurse Researcher
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 19, 2023
First Posted
April 17, 2024
Study Start
October 6, 2023
Primary Completion (Estimated)
May 31, 2027
Study Completion (Estimated)
December 30, 2027
Last Updated
February 17, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will not share